Vol. 3 No. 3 (2018): VESTNIK of KSMA

Resume: The study shavis the incidence of H. infection in the republic presentsdurig 2013-2018 years. It presents as a result of preventive measures, the incidence of Hib infection tends to decrease. The study of the resistance of the Hib antimicrobials identified resistance to some B-lactam antibiotics. But in connection with the features development of the Hib infection, antibiotics should be ahhlied against all representatives of the isolated micrjbial association.

Abstract. The study of the medicinal properties of the flowers of the immortelle Samarkand growing on the territory of the Kyrgyz Republic has a great future. The effectiveness of the flowers of the immortelle Samar­kand is mentioned in the folk medicine of Kyrgyz people. The sources describe the technology of preparationand methods of application of flowers immortelle Samarkand. Therefore, the analysis of the effectiveness of the flowers of the immortelle Samarkand growing in the Kyrgyz Republic is of great interest for science and practical medicine and is relevant today.

Summary: The investigation showed that microcirculation has own pecularities in different forms of progres­ sive ischemic brain lesions. Original dynamic changes of amount deusity, hole and cross-section square of vessels were revealed. General cross-section of standard venous value may be used as diagnostic indicator of venous stagnation development revealing in different level during whole investigation duration. Destructive changes originate in the counterpart (intact) brain hemisphere.

Resume: The randomized controlled clinical trial for evaluation of efficacy of Vifex syrup on parameters of global health assessment and quality of life of pulmonary in-patients with moderate or severe acute/subacute cough was conducted in National Center of Cardiology and Internal Medicine. In comparison with patients in control group, addition of Vifex syrup to the main therapy regimen in experimental group after 5th day of therapy resulted in clinically and statistically significant improvement of cough frequency and severity (meas­ ured by VAS), cough daytime intensity (measured by verbal range scale of Cough daily intensity diary), and physical constituent of quality of life of patients (measured by Leicester Cough Questionnaire). Obtained data demonstrates efficacy and safety of Vifex syrup in relief of unpleasant symptoms severity in comparatively short time and significantly improvement of global health status, nocturnal sleep and quality of life in patients with persistent distressful and annoying cough.

Summary: Cases of food botulism are registered in the Republic annually, often occurring in severe form and may be fatal. This article analyzes 24 cases of patients with severe forms of food botulism. The diagnosis was confirmed by clinical, epidemiological and laboratory with reaction of neutralization in mice. The toxins A, B, C and E were isolated. The disorders of swallowing and breathing are important in severe form of botulism, as well, as late diagnosis. Improvement of the state and regression of neurological symptoms in severe botulism occurred for 2-3 weeks of the disease.

Summary: In the article the characteristics of the dynamics of the incidence of brucellosis in people after the implementation in 2010 of vaccination of small ruminants (sheep and goats) in the Kyrgyz Republic. The absence of vaccination of cattle maintains the disease at a still high level, as evidenced by the increase in acute forms of brucellosis in the last two years. The clinical picture was studied on the example of hospitalized patients in the Republican clinical infectious diseases hospital in Bishkek.

Summary: Abstract: the article analyzes the etiological structure of severe forms of viral hepatitis on the example of patients admitted to the intensive care unit of the Republican clinical infectious diseases hospital in Bishkek. The age aspect of the sick, epidemiological anamnesis, clinical symptoms, concomitant pathology laboratory data were studied in detail. Identified the prevalence (37%) undifferentiated viral hepatitis, hepatitis of other etiology, with the highest frequency (92.9%) of deaths.

Resume. The article presents the results of rehabilitation programme for children with Idiopathic Thrombocy­ topenic Purpura (ITP) in the settings of mid- altitude (1760 meters) with subsequent treatment programme in high altitude in-patient care Tuya-Ashuu hospital (3200 meters). Out of 12 children received high altitude climate therapy, 2 children achieved - full remission, 7 children achieved - partial remission, 2 children showed transient improvement of clinical-hematologic indicators. Complete absence of the effectiveness was recorded in 1 child. Significant positive clinical results achieved in majority of patients in high-altitude settings persisted in the long term (during 6 and 12 months). Conclusion: Clinical-hematologic remission achieved in 75% children and 62% adults.

Abstract: To prevent complications of diabetes mellitus 2, it is necessary to achieve normoglycemia by opti­mizing treatment. One of them is the introduction of new generations of drugs, for example, an inhibitor of dipeptidyl peptidase-4 in combination therapy. Advantage is not only the elimination of metabolic violations, but also the preservation of pancreatic cell activity and stimulation of insulin secretion. The article presents a modern analysis of the literature on the efficacy and safety of dipeptidylpeptidase-4 in combination therapy and its own experience in its use.

Summary: Yersiniosis infections are widespread, characterized by significant polymorphism of clinical man­ ifestations with damage to various organs and systems. The article analyzes the clinical and laboratory features of the diagnosis of pseudotuberculosis and intestinal yersiniosis in 30 patients hospitalized in the RCIM during 2015-2017. The cause of infection was consuming of fresh vegetables, fruits and salads. Clinical picture didnt change its classical features even contemporary diagnosis and also in adequately conducted etiotropic therapy it was characterized by uncomplicated course with subsequent recovery.

Abstract: On the example of a clinical case was demonstrated the possibility of diagnosing an icteric form. The Diagnosis of leptospirosis depends on depth analysis of clinical symptoms, which not always have a typ­ical picture and modern diagnostic methods: enzyme immunoassay, polymerase chain reaction

Summary: The article presents the results of analysis of the evaluation of neuroimaging and haemostasiograms in patients with acute and preacute cerebral infarction receiving treatment in the Department of Angioneurology of State Clinical Hospital No.1.

Summary: The results of clinical and epidemiological observation of 54 patients with mumps are presented in this article. These patients were hospitalized in the Republican hospital of infectious diseases in period 2015­ 2017 years. The analysis of the obtained data showed a more frequent occurrence of the disease at the age of 15-20 years and an increase in combined glandular forms, including 40,7% with orchitis. The epidemic rise of mumps is observed in the winter-spring period.

Summary: There are given the methodical bases of performing persistent cannula free tracheostome in per­sistent stenosis of larynx resection preventing from complications from cannule tracheostome.

Summary: To assess the results of traditional organ-preserving surgeries and the results of the method of abdomination of the fibrous capsule in 180 patients. In 77 patients the method of capitonage and invagination was used, omentoplasty according to R.P. Askerkhanov and 103 patients underwent abdomination. After capitonation and intussusception, complications occurred in 15 (19.5%), and after complication abdomination in 10 (9.7%). There were no lethal outcomes in both groups.

Resume: The article cites the case of expert practice on establishing the couse-effect halation ship of the onset of death 8-9 days after receiving multiple fractures of the ribs. The cause of death had several mediated, related pathological processes with the visiting trauma fractures of the ribs-pain syndrome-superficial paradoxical breathing-secretion of the secretion in the bronchial tubes de­velopment of the “wet lung” syndrome - impairment of the respiratory function-circulating disturbance - stag­nation in a small circle - cardiovascular insufficiency - death.

Resume: A retrospective analysis of the case histories of 67 patients with intestinal anastomoses was carried out. There were 42 males and 25 females, the age of patients ranged from 25 to 78 years, an average of 62 ±1.7 years. Total complications revealed 11 (16.3%), including wound, intra- and extra-abdominal. In the post­ operative period, inconsistency of the intestinal sutures was noted in 6 (8.9%) of 67 patients, 2 (2.9%) died.

Resume: Results of 22 patients with pancreatonecrosis, which were operated with the use of drug therapy before and after the operation, are given. The first group (10 patients) received traditional therapy, and patients of the second group included antibiotic-lymphotropic mixture and total ozonotherapy (12 people). The best results were obtained in the second group.

Summary: There are shown results of operative treatment of echinococcosis of the liver in 188 patients, who been radically operated (42 persons) and Organ saving operation (146 persons). In the short time we have found 4 (9.5%) patients with complecations who had been radically operated but there were no cases of echi­nococcosis Relapse. After organ saving operations, we have found complications in 18 (12.3%) persons, Re­lapse echinococcosis were found in 3 (2.1%) persons after 2 years.

Resume: There were presented the results of the oesophagocardiomyotomy on Geller-De Brune Groeneveldt in 16 patients at the age of 18-66 with the achalasia cardia (AC). Male - 6, Female - 10. The disease duration from 1 year to 6 years. The 3rd stage of the disease was confirmed in 12 of the patients, 2nd stage - 4 patients. The confirmation was made by fluoroscopy of the esophagus and gastroscopy. Oesophagocardiomyotomy was made in our clinic to 13 of the patients by laparotomy access. 3 patients were performed the oesophagocardi-omyotomy with anterior gemioesophagofundoplication by Dor techniques using of endo-video surgical tech­ nologies. During the surgery and in early post-surgery periods a specific complications related to the surgery were not detected. Lethal cases are absent. Long-term results were studied among 10 patients (from 6 months to 5 years). All of the patients felt satisfactorily, dysphagia and pyrosis were not detected, recovery of weight and improvement of general health condition were observed.

Annotation: In this study, statistical analysis of data on epidemiology, the effectiveness of surgical treatment, and the further quality of life with metastatic brain lesions over the past three years (2015-2017) was used. With the improvement of early diagnosis, which provides timely detection of solitary, miliary and small metastases, leads to the conclusion that, at the slightest cerebral symptomatology, it is necessary to diagnose for the presence of metastasis in the brain. Over the years, the frequency of treatment of patients with metastatic brain lesions has increased in the Kyrgyz Republic. Thus, rational surgery of tumor metastases in the brain can be considered a method of choice, which allows to increase the duration and improve the quality of life for operated patients.

Conclusion: During retrospective analysis of 84 women, the main group consisted o f 35 who got a standard therapy and a balloon tamponade (BT), in control included 49 w ho received a standard therapy. The effective­ness o f BT evaluated with indicators; patient satisfaction evaluated on a 10-point scale.

Summary: Research o f 100 breast and early age children, the inhabitants o f the Kirghiz Republic various regions receiving hospitalization in The National Center o f welfare o f motherhood and childhood concerning acute bronchopulmonary pathology is carried out. It is defined, that in investigated groups there is a consider­ able number o f cases o f the nutrition status disorders with relative density increase with the years. The m ost significant mistakes in the food organization o f children o f 0-6 months, 6-12 months, 1-2 years are revealed. B y comparison o f groups o f often and rather seldom ill children, the greatest relative density o f mistakes in the food organization o f children in the first group is established.

Summary: This article reflects the results of improved bone plasticity of the defect of the alveolar process of the upper jaw by the example o f 60 patients who received surgical treatment in the m axillofacial department of the Osh Interregional United Clinical Hospital.

Resume. The article deals with the inclusion o f adaptation-compensatory mechanisms for partial adentia and their changes in comparison with intact dentition.

Summary: The article presents the results of a study to identify risk factors for the occurrence of dental dis­eases in children and adolescents playing on wind instruments (Bishkek).

Summary. There have been investigated methods o f chronic destructive apical periodontitis treatment with the use o f a gold nano-solution, which is considered to be the m ost effective due to its reparative properties in conjunction with calcium hydroxide, influencing the fall o f destructive loci in the apical part o f the root of a tooth.

Resume: This article describes elective course that provides the teaching of the Latin language at medical higher educational institutions. Also this article considers organizing and conducting elective courses, course subjects and their role in the training of future doctors.

Resume: New pedagogical methods o f foreign languages teaching, particularly «Teaching in collaboration» are presented in this article. Different variants and principles o f «training in collaboration» are given.