Vol. 1 No. 1 (2018): VESTNIK of KSMA

Abstract. The work is devoted to the study of clinical features of CMV infection in children up to the first year of life and up to 15 years. Clinical manifestations with conjugation jaundice, hepatosplenomegaly, anemia, malnutrition, hypertension-hydrocephalic syndrome, bronchitis, pneumonia, hemorrhagic syndrome, prematurity, cerebral calcifications thrombocytopenia fetal biliary atresia were found. More than half of infants under 3 months were CMV positive.

The article presents the results of dynamic monitoring of the functional status of foreign students by using mathematical analysis of heart rate variability at various stages of academic year – autumn and spring educational semesters, winter and summer examinations. Strengthening the influence of the parasympathetic department of the autonomic nervous system was revealed during the intersessional period – the autumn and spring time of the academic year. In the winter examination session, the contribution of the sympathetic spectrum to the regulation of the heart rhythm was noted, in the summer session, an even greater shift in vegetative balance towards the sympathetic link of the VNS and an increase in the degree of centralization of the heart rhythm, indicating emotional stress and a functional imbalance in the cardiovascular system of students.

Evaluation of the clinical efficacy and safety of the drug Ecdyphyt as an adaptogenic and anabolic agent was carried out in patients with pulmonary tuberculosis.The research included 200 patients of both sexes aged from 18 up to 60 with the verified diagnosis of a disseminated, focal, infiltrative pulmonary tuberculosis and an exudative pleurisy of the tubercular etiology.Administration of the drug Ecdyphyt does not aggravate the condition or state of health caused by side effects of the drug. It was determined that using Ecdyphyt as an anabolic and adaptogenic agent in a complex therapy of the pulmonary tuberculosis increases the treatment efficiency.

Abstract: One of the prospective directions in a local treatment of surgical infection is the use of ointments based on herbal essential oils which advantages are indisputablein comparison with synthetic analogues, and are as follows: good tolerance, few side effects, a possibility of prolonged use, a lownumber of contraindications. Thus, clinical research of the developed new plant medicine Ayafrol, 3% Ointment is relevant in treatment of a wound infection. In the given article, data on 1 phase of clinical trials of Ayafrol are presented.

Resume. Starting from 2010 every year on May 19 the whole world celebrates the World Family Doctor Day. This event was firstly announced as a World Day by the WONCA, the World organization of family doctors. The aim of the World Day is to promote comprehensively the modern understanding of the role of family doctor as a leading specialist of the whole healthcare system. Effectiveness of the primary, secondary and tertiary level depends on the work of family doctor. The article describes experience of conducting World Family Doctor Day in various countries including Kyrgyzstan.

Resume: the article presents the results of treatment of 62 patients common psoriasis vulgaris, which were distributed by the method of treatment in 2 groups: control (n = 30) and primary (n = 32). Along with conventional therapy, the patients received basic group Timotsin, L-carnitine and Afobazol that resulted in normalization of T-cell immune system and immunoglobulin A and G, and reduce levels of anxiety normalization of depression. PASI scores decreased from baseline equal to 34,1±2,4 to 6,7±0,7, which indicates a good clinical effect of this therapy.

Resume. To study the level of awareness of nursing specialists, 48 nurses working in the National Oncology Center in Bishkek and 50 patients were interviewed about the basics of palliative care and the degree of patient satisfaction with nursing care. The inadequate level of professional training and motivation of nurses to care for incurable patients is established. It was revealed that the overwhelming majority of patients were satisfied with nursing care. The importance of training at all levels of medical education in the organization of palliative care has been determined.

Summary. This article is considered the effectiveness of motivational support patients MDR TB in the treatment with SLD in Kyrgyzstan. In comparative study of effectiveness of the treatment (Р>0,05) using only the treatment of tap with patients, in addition treated motivational support, there was no statistically significant differences on the outcome “the success of treatment” (55,3% и 55,0%) and “default” (18,6% и 22,3%).

Summary: The article presents the immune status of patients with infiltrative-suppurative trichophytosis before and during treatment timogen. Before treatment there leukocytosis, imbalance of T cell immunity, increased Ig M, G in both groups of patients. After treatment, the percentage of CD4 + - cells normalized in both groups. Thus CD3 + did not reach to healthy individuals, but in the test group showed significantly higher content of compared to the control (p <0.05). Dates disappearance of clinical manifestations of infiltrative-suppurative trichophytosis in the main group, where timogen applied, advancing by 5 days earlier than the control group.

36 patients with a primary and secondary pterygium were examined for studying the relationship between the morphological changes in the pterygium and the state of tear production. The hyperproduction of tears in the primary pterygium and the picture of vasculitis with a recurring pterygium were revealed.

We analyzed results of operative treatment of 246 patients with abdominal pathology. In the early postoperative period developed venous thrombosis of lower extremity. Timely nonmedical and pharmacological treatment, prevention of thromboembolic complications in abdominal operations prevents pulmonary embolism.

Resume: given results of operative treatment of 300 patients with acute and chronic cholecystitis, operations were performed from minilaparotomic access. 3 from 130 patients with acute cholecystitis and 2 from 170 patients with chronic cholecystitis had transition to conversion. 11 patients (8.5%) with acute and 7 patients (4.1%) with chronic cholecystitis had complications. There were no fatal cases.

Summary: New developments of operative and conservative treatment of herniated intervertebral discs are presented, in a comparative aspect with traditional methods.

Summary: the purpose of this research is to represent the results of echinococcectomy, which been performed in 125 patients who suffer from echinococcosis of the liver. In addition, control group from them was 62 (49,6%), and the main group had 63 (50,4%) patients. The traditional treatment had been performed in the control group, but in the main group, we had taken a different way of curing, the method of the irrigation of the residual cavity of the fibrous capsule with an ozonized sodium chloride solution with a concentration of 8-10 mkg/mg and decasaniin 0,02% intra venously 1,0 cefazolin or 1,0 ceftriaxone, and after the operation, aspiration was performed from the cavity of the fibrous capsule. In the main group there were 3 (4,8%), and in the control group 7 (11,3%) complications.

Summary: aim of study: to assess effectiveness of infrared exposure in prophylaxis of wound complications. Presented results of prophylaxis measures in 102 patients of control group by using traditional measures and in 83 patients of main group where used infrared exposure in prophylaxis of complications of wound infection. In control group complications were in 15 (14,7%), in main group in 4 (4,8%).

Abstract: Results of surgical treatment of 54 patients with cholelithiasis associated with thyroid gland disease are presented. Among 54 diseased there are 51 (94,5%) are women and 3 (5,5%) are men. Age ranges from 20 to 70 years of age. All patients had simultaneous surgical treatment (cholecystectomy + thyroid resection). The efficiency of simultaneous surgeries at these diseases has been proved.

Resume. The work presents data comparing the use of measures to reduce pain after laparoscopic cholecystectomy using traditional medicines and our improved method. In 79 patients after laparoscopic cholecystectomy, analgesics were used intramuscularly, and in 68 patients, an improved method was applied. The comparison showed a higher efficiency when using an improved method.

Resume. In this literature, review questions of definition, etiology, pathogenesis, clinic and treatment of sepsis are considered. The literature data of the authors of near and far abroad are presented.

Summary. The purpose of research – Improving results of surgical management for spinal cord injury by perfecting diagnosis and surgical methods.

Object of research: 102 patients with spinal cord injury. Methods of investigation: neurological, radiological, computed tomography and magnetic resonance imaging of the spine.In the work the peculiarities of clinical neurological displays of spinal cord injury have been studied, comparative analysis of various diagnostic methods efficacy was done, the structure and ways of prevention for postoperative complications have been investigated. Special device and way for surgical treatment in spinal cord injury have invented. Complications of traumatic disease of spine and spinal cord, surgical management ways have been update. The new ways for prevention and surgical management of such a complications proposed.

Summary: The results of endoscopic examination of esophageal-intestinal anastomosis in patients with gastric cancer, operated in the volume of gastrectomy with different variants of small intestinal plasty, were studied. Only 51 patients were divided into 3 groups. A significant decrease in esophagitis (p <0.05) was found in the group of patients with the formation of the jejunal pouch reconstruction after total gastrectomy for cancer.

Summary. Minimally invasive surgery – removal of hematoma content through an opening by lavage of its cavity followed by dosed external drain – has been performed in 112 patients with chronic subdural hematomas (CSH). Out of 112 patients subjected to sparing surgery, hematoma and its capsule resolved within 1-3 months in 60 (53,6%). Mortality was decreased from 2,6 to 1,1%, incidence of intracranial complications from 35 to 7,5%. The draining shortened the hospital stay of CSH patients by 20%.

Resume. The article describes the questions about the secondary deformations of dentition, arising on the background of periodontal tissue diseases and the need for an orthodontic stage of treatment. There is describes the applied non-removable and removable orthodontic devices, the advantages of removable orthodontic appliances.

Summary: expands the possibilities for optimal use of the diagnostic equipment and Cad Cam system for rational implants and prosthetics.

Summary: In 120 pregnant women with chronic pyelonephritis, an assessment of the course of pregnancy and kidney function in the third trimester of pregnancy – the main group. Women of the main group more often showed somatic diseases, in the structure of gynecological diseases prevalent chronic diseases of the appendages. The course of pregnancy was more often complicated by miscarriage and hypertensive disorders of pregnancy, premature birth, development of FPN of the fetus. When analyzing the functional state of the kidneys of the examined women, a significantly decreased GFR and clearance of creatinine

Summary: In this research, work was dan analyzes the 45 history labors in pregnant woman with tuberculosis, which entered to the Municipal perinatal center duration 2004-2017 years. It is educated, that for 11% women with tuberculosis was confirmed et the heavy degree of diseases. In anamneses at this contingent of women, the infected by tuberculosis was dan in the first and second trimester of pregnancy. The disease was current without clear of clinical symptoms. Worsening of severity diseases happened in the third trimester of pregnancy, post delivery times and in 4% cases an end was lethal.

Summary: Retrospective analysis showed that in women with inflammatory diseases of the reproductive system, the frequency of obstetric hemorrhages is 2,5%. In this group of patients, anemia (3,7 times), cardiovascular system diseases (2,9 times) and urinary system (2,0 times) were diagnosed more often. Of the gynecological diseases, erosion of the cervix (3,0 times), colpitis (2,7 times), endocervicitis (2,6 times), chronic salpingo-oophoritis (2,3 times), chronic endometritis (1,9 times).

Summary: The structure of the incidence of intrauterine infection (IUI) in newborns was studied by retrospective processing of their case histories. It was revealed that the highest rate of occurrence was observed with herpes simplex virus (HSV) – 86% and cytomegalovirus infection (CMV) infection - 85%. Risk factors for the development of IUI in newborns are maternal illnesses during pregnancy, such as malnutrition, anemia, acute respiratory viral infection, and hyperthermia. It was found that the risk of developing IUI is higher in boys than in girls, in premature babies, in newborns with a more severe course of the disease, and also in hospitalized in the late term. Clinical signs of IUI were most pronounced on the part of the digestive organs – 86% and the central nervous system – 42.3%, less than the respiratory system – 27%.

Summary: The article provides a review of literature on the factors of the formation of eating behavior stereotypes, the peculiarities of eating behavior of children and adolescents of school age, and its importance in maintaining and strengthening health.

Resume: The clinical data of children with craniocerebral trauma at a child abuse syndrome (age structure, complaints, clinical manifestations, results of functional examination methods) are presented in the article.

Summary: A comparative clinical study of Lactiale (sachet) was conducted. Two groups of patients were observed with a total of 60 children aged 1 month to 1 year with moderate secretion diarrhea who received treatment in the intestinal department of the Republican Clinical Infectious Disease Hospital (RCIB). 30 patients were received the Lactile Toddler, and 30 patients who did not receive this drug were in the control group. Analysis of the frequency and duration of the main clinical signs in the observed patients in the compared groups showed that frequent vomiting – (36,4±12,4%, 80,8±8,5%), body temperature (1,8±0,5, 4,0±1,0 days), stools (2,1±0.5, 3,9±0,8 days), hospital stay (2,1±0,5, 3,9±0,8 days), were longer in patients of the control group.

Summary: The article presents data on the mortality rate of the able-bodied population of Osh and Osh region for 2000 y. It was found that the cause of death of the largest number of deaths according to the Osh regional bureau was the pathology of the cardiovascular system (16.9%) and predominantly in men 12.4% against (4.5%) of women. A significant proportion of deaths occurred in the age range from 26 to 55 years (17.9%), with an age of 36 to 45 years – 8.4%. No less critical is the age from 56 to 65 (7.3%). According to ethnographic evidence, the prevailing majority of the deceased were Russians (50%), and Uzbeks (26.08%), Kyrgyz (17.39%), Tatars (6.53%), which is due to the refusal of local residents to open corpses for religious reasons.

Summary: In 2013, 609 cases were registered, of which 44 were returned without execution. According to the materials of criminal cases 357 (58.6%), civil cases 10 (1.6%), according to the rejected material 242 (39.7%) cases. In 36 (5.9%) cases, the examinations were primary. The main reasons for the appointment of examinations were the establishment of the degree of harm to health. The basis for the production of examinations in the main were the decisions of law enforcement agencies. For 2014, 772 cases were registered, of which 50 cases were returned without execution. Examinations, mainly, were conducted on the basis of materials of criminal cases and on the basis of decisions. On the floor under the expert were mostly male. For professional offenses of health workers, both in 2013 and in 2014, examinations were conducted, mainly, with regard to obstetrician-gynecologists.

Summary: The analysis of commission forensic examinations for 2013-2014 years of professional offenses of medical workers. It was established that the final part of such examinations was carried out in relation to obstetrician-gynecologists (41.9%), surgeons (12.45%). Of the 129 examinations in 92 cases, the examination was carried out based on the materials of the refusal cases and only in 35 cases on the materials of the criminal cases the identified defects in the provision of medical care were associated with diagnostic and treatment, incorrect tactics of giving birth, and incorrect implementation of operations.

Resume: The article gives an analysis of the frequency and structure of gunshot wounds and blasting injuries. It is established that out of 7856 (100%) investigated corpses in 2012-2016 y. as a result of gunshot wounds and explosive injuriens 72 people died (0.91%). Among the deaths in 68 cases (94.4%) were men, and in 4 cases (5.4%) were women. The analysis showed that gunshot wounds and explosive injuries are more likely to kill people of young and working age from 17 to 66 years 67 cases (93.1%). Often alcohol is also found in the blood, 14 cases (19.4%) and alkaloid opium 10 cases (13.8%).

Resume: The article gives an analysis of the frequency and structure of deadly road - traffic accidents according to the data of the RCSMM Ministry of Health of the Kyrgyz Republic for 2014-2016. It was found that the incidence rate of an accident during the study period was 175 cases (3.9%) of all deaths during the study period, totaling 4,438 (100%). Of these, for males, there are 109 cases (62.3%), for women, 66 cases (37.7%). It can also be noted the frequent mortality of young people aged 17-26 years 36 (20.5%) cases for the study period, as well as people of working age from 17-66 years 144 cases (82.1%). Often alcohol is also found in the blood, 56 cases (32.0%) of 175 (100%) for the study period

Resume: The article contains data on the analysis of the deadly auto trauma for 2000 and 2007-2010. It is established that for the analyzed years only 8659 (100%) forensic medical investigations of corpses were carried out, of which 436 deaths (5.03%) were caused by auto-trauma. The most common causes of death were cerebral trauma 247 cases (56.6%), followed by traumatic shock 90 cases (20.6%) and blood loss 34 cases (7.8%). From auto-trauma more often male faces die in young and working age from 17 to 58 years 358 cases (82.0%). In the state of alcoholic intoxication, 165 (37.7%) of the deceased were in various degrees, in 1 (0.2%) cases in the state of intoxication. There are a significant number of deaths in autumn and winter (148 cases in autumn (34.0%), winter 107 cases (24.5%), respectively).

Resume. The study of sources that have come down to us showed, that in past on the territory of Kyrgyzstan people accumulated and cultivated various knowledge and skills in healing. Tabib was only bearer of centuries of experience in the fight against disease in all it is scope, because he was in one person and healers and pharmacists. Tabibs were divided into pulsars (tumirchi), bone caries (sinikchi), herbalists (chopchy) and midwifes (unuchi). In Manas epic there are information about tabibs, that treat herbs with animals and minerals products, about methods of treating bone fractures and the use of smile surgical instruments (ushtur, tintuur, shuk-shuk etc.). The ordinarily folk medicine of the Kyrgyz people, which was formed by the Kyrgyz people for centuries, should give a unique reflection in the concept integration of folk and modern medicine of Kyrgyzstan.

Resume. Despite results of multi-purpose and long-term interaction and relationships with other peoples as well as the deep interaction of other people’s medicine, folk medicine of Kyrgyz people is original. There are their original methods preparation of medicinal forms from medicine plants, their drying and storage, which arose on the basis of ethnographic and geographical features of Kyrgyzstan. This finds confirmation in the lines of the epic “Manas”, called by the famous writer of our era C. Aitmatov “encyclopedia of the Kyrgyz people” often there are groups of medicines, which include epic medicines that belong only to Kyrgyz.

Resume. In article considered guestions about teaching Kyrgyz language, directly concerning for future generation.

Resume. In this article there are medical euphemisms. Self-study management is responsibility and activity of each teacher.