Vol. 2 No. 2 (2012): VESTNIK of KSMA

This paper presents information on the prevalence of injuries in the Republic. Summarizes the level, structure and causes of injuries.

In this research opportunity and effectiveness of carry out simultaneous and combining operations in short time stay in hospital proved

In analysis of the level, causes and structure of perinatal mortality in Kirgiz Republic for last 10 years showed possible ways of decrease there’s in modern conditions.

of this study was to determine annual age lung function decline in COPD patients, exposed to chronic intermittent hypoxia. Materials and methods: 58 COPD patients aged 46.3 ± 5.8 years were included into this 4-year prospective study along with equal number of healthy subjects working at altitude 3800-4500 meters in Kyrgyzstan Results and conclusions: There was a marked reduction of all lung function indices in COPD patients group, including forced expiratory volume within the Ÿrst second (FEV1) – from 88.2 to 81.8% predicted (81 ml a year), whereas in healthy subjects group – only 58 ml a year (p < 0.001). Thus, COPD patients arriving or working at high altitude must be recommended to limit the time of exposure.

The analysis of knowledge level among patients as well as impact of elaborated educational program on their сonception about the disease and ways of treatment along with analysis of survival rate of knowledge in 5 years after training was conducted in the frames of activities of “the School for the patients with ulcer disease”.

We survey 699 patients who had laparoscopic cholecystectomy to 2006-2011 in National surgical center MH of the Kyrgyz Republic. Patients have been divided into 2 groups: patients aged are more senior 70 years (group A) and patients are younger than 70 years (group B). The group A has been divided further into 3 age subgroups: 70-74, 75-79 and 80 years and more senior. Estimation on scale ASA increases with age increase (P <0,001). At patients at the age of 80 years and more senior, at an acute cholecystitis conversion and postoperative complications were considerably above, than at younger patients (P> 0,05).Quality of results of laparoscopic cholecystectomy in group of patients >80 years it has appeared not more low, than in group of younger patients. Complications can be minimized at careful selection of patients aged >80 years, and operation carrying out by the skilled surgeons having high technical skills. 

The results of radical operations of liver gemangioma in 11 patients were presented. Complications were marked in 5 patients, without fatal results.

results of radical operations of liver echinococcosis in 29 patients were presented. Resections of liver was made in 17 patients, resection-enucleation - 3, total pericystektomy – 9. Complications were marked in 6 patients, without fatal results.

This article covers research of effect of Adaptol® drug to psychic constituent of disease at patients with myocardial infarction. The research was carried out on the basis of cardiological clinics BelMAPO and it was included 35 patients of male sex with diagnosis of acute macrofocal myocardium (Q-infarction).It was made a conclusion on positive effect of Adaptol® drug to subjective state and objective criteria characterizing psychic constituent of disease at patients with myocardial infarction.

The overview of pharmacological properties of H1-antagonists was made on this paper. The conclusion was done, that for most clinical applications in outpatient conditions the drugs from II generation (“non-sedative generation”) are drugs of choice because they haven’t got any sedative properties. Fenkarol® (Quifenadine) has unique properties to accelerate destroying of histamine and to deplete it depot in tissues. Due to these properties Fenkarol® is one of the drug of choice from H1-antagonists for acute respiratory diseases treatment (common cold) and in complex medication for the treatment of bronchial asthma. As well Fenkarol® is one of the drug of choice for pediatric practice owing to the safety and long clinical experience of its use.

The results of examination and surgical treatment of 216 women with genitals prolapsed are presented. An objective examination and USI are the main diagnostic methods. The choice of the operation depended upon the degree of falling and prolapsed of vagina and uterus, and it depended upon the condition of pelvis fundus muscles, too.

It has been done monitoring of susceptibility/resistancy leading pathogens of urinary tract infections isolated from 475patients in different institutions of Bishkek during 2008-2010. It is exposed the tendency of decreasing the role of Gram-negative icroorganism in developing the urinary tract infections and predominance position of Enterococcus. The analysis of the antibiograms exposed absence of susceptibility uropathogens to penicillin, ampicillin and selective susceptibility to cephalosporins of different generations. The drug of choice is suggested cipro(oxacin.

Dental treatment of patients with common somatic pathology can cause complications in these patients or causes unsuccessful outcome during dental treatment. That is why knowledge of these moments is the base prophylaxis of undesirable comlications. Questionnaire of dental patients deǎning risk of stomatological interventionand recommendations to admittance of patients with cardiovascular pathology are given in this article. According to different authors among ambulatory patients 30% of patients has different common somatic diseases in compensated forms. Dental treatment of these patients may in(uence their state complicating the course of attendant diseases, or accompanying pathology may lead to unsuccess of dental treatment causing different complications during dental manipulations or after treatment. That’s why it is necessary to carry out carefully the treatment of these patients.

Analyze the hemodynamic performance mexidol 23 patients with age-maculodystrophy retina (AMD) before and after 20 days of treatment at different stages of AMD, using Doppler ultrasound. Revealed the highest efɨcacy at a stage of AMD.

The in(uence of β1-blocker atenolol on hemostasis in experimental cathecholamine myocardial injury and high altitude mountain conditions was studied. It was established that in experiments, atenolol produces moderate hypocoagulation thereby causing beneŸcial effect on hemostasis in acute myocardial infarction.

neuropeptide cortexin has universal neurometabolic and neuroprotective action. Our investigation is devoted to the effectiveness of cortexin discircular encephalopathy. 54 patients were examinated, 30 patients are the main group and 24 control. The main group patients got cortexin and based therapy, patients of the control group got magnesium sulfate. The assissment of treatment results was carried out using clinical and neuropsychological study methods. On the background of cortexin therapy it was marked the improvement of subjective and objective data in many patients. In 90,3% of patients it was marked the decrease of subjective symptoms intensity: emotional lability, anxiety and depressive reactions, fatigability headache. Cortexin may be recommended as neuroprotector not only in cerebravascular deseases but in pathological conditions accompanied by impairment of cognitive brain functions

Nutrition status and daily eating habits of Kumtor workers were studied. It was found that food consumption was reduced in autumn and winter, hence basic nutrients consumption was also decreased. White collar and medium labour employees showed basically protein nutrition proƑle.

Authors described results of experimental research. The aim of this work was to study Cerebrolysin’s in(uence on brain structure pathological changes in the earliest posttraumatic period. The experiment was based on moderate brain injury experimental model using rodent animals. The trauma caused at animals complex of macro- and microscopic pathomorphological changes. Their analysis demonstrated deĸnite stages in these pathological changes development. Cerebrolysin lead to regression of pathomorphological changes in the early posttraumatic period (at 14th day after trauma). In the control group of animals was used physiological solution. Its curable effect on the cortex neurons was not veriĸed. Results of this experiment are reason for the effectiveness of Cerebrolysin using in the therapy of patients with traumatic brain injury.

There are the results of Hypofur salve of wound healing efĔciency the new drug made in KG, in II phase of woundhealing process in experimental conditions «in vivo».

The results of examination of patients with ĸrst degree postgastrectomy enteral insufĸciency with complicated ulcer of stomach and duodenum are represented in this work. Cavitary and parietal digestion of stomach and jejunum and blood enzymes with modiĸed application of enteral feeding have been investigated.

The review article is devoted to the actual problem of assessing the psycho-physiological state students.

This article focuses on the use of pharmacoeconomic and pharmacoepidemiological analysis as the most effective method of determining the value of different methods of treatment, the choice of the optimal method of reatment.Pharmacoeconomic studies and Pharmacoepidemiological in therapy for respiratory diseases allow to compare different treatment regimens, to determine the need for new, expensive drugs. This ensures the rational use of funds for the most effective therapeutic treatment.

Introduction of international standards GMP, GLP and GCP is real necessity, and positively in䮠uences quality of made medicines.

The peculiarity of the pharmaceutical market is that it is one of the most proŸtable & fast growing sections of the world economics. In Kazakhstan there is a plan to provide domestic market with 50% of our own production. The peculiarity of new production is that they are planning on international GMP standard that give a possibility in future to expect this production in any country of the world.