Vol. 2 No. 2 (2017): VESTNIK of KSMA

Resume. Mirsaid Mirrakhimov is a founder of the school of cardiologists, pulmonologists, nephrologists, hematologists, rheumatologists, gastroenterologists of our country who made a huge contribution to the investigation of high altitude medicine. Prominent scientist, extraordinary physician, seeking physiologist and pathophysiologist.

Epidemiological analysis of epidemic parameters and main evidences of HIV infection epidemic process in the Kyrgyz Republic as of the end of 2015 were given in this article. Nowadays intensive development of HIV infection epidemic is observed in Kyrgyzstan. For a period from 2003 to 2015 infection prevalence rate was increased by more than 6 times (from 10 to 68 per 100 thous. people of population).

Summary: Variants of profile of lateral serebral organization and progress indices of 320 students of the I-III courses in the faculty «General medicine» at the age of 18 to 22 were studied. Profile of lateral serebral organization according to the scheme «hand-foot-ear-eye», and also students progress according to the results of exams were determined. It is revealed that to the third year of training variants with left signs of students profile of lateral serebral organization have been increased. Indices of the 3rd year students progress are increased as in girls so in boys.

Summary: The article presents the values of cardiointervalogram indicators the college and lyceum's students of humanitarian, medical and technical specializations. There had been investigated 240 students aged 16-17 years. Determining the level of body's vegetative supporting functions carried out by means of physical activity-Martin sample.This test was carried out in 2 stages: 1) state of rest in a sitting position (the registration of cardiointervalogram was carried out for 5 minutes)-background indicators; 2) after 20 squats for 30 seconds (recording with CIV for 5 minutes). Before the prior sample the normotonics were dominated among boy and girl students (78% and 73 respectively).The vagotonic reaction was observed in the boys'health of the technical specialization (25%) and in girls'health of humanitarian specialization (23%). In the boys' health of the humanitarian specialization prevailed simpatikotonik (65%) and ingirls' health of technical specialization (42%).
Comparing the types of vegetative tone obtained during the Martine tests there had been revealed that in the health of the surveyed students of medical lyceum dominated normo tonics (75% and 70% respectively). The vagotonic reaction was observed in health of boys and girls (8% and 5 % respectively) and in the boy's health of technical specialization (5%).Noticeable simpatikotonia was found in health of girls of the humanitarian specialization (33%) and in health of girls of technical specialization (12%) that indicates the activation of the sympathetic nervous system. During the analysis of the cardiointervalogram indicators it was determined that at the end of first year the students of medical and technical specialization were more adapted to the training loads of the colleges and lyceums. According to the investigation we can suppose that to the vegetative supporting functuions of the students are influenced by the training specifics and individual features of surveyed students.

Summary: This article presents data on the study of quantitative parameters of blood in patients with neurooncological 802 for the period of hospital treatment in the National Hospital of the Ministry of Health of the Kyrgyz Republic from 2010 to 2015. It was found that living in the area of uranium tailings, anatomical and topographical location, primary or secondary neoplastic lesion of the process and its degree of malignancy are some statistically significant features of blood indicators.

Resume. The article is an international experience in hospital pharmacy. Studied hospital pharmacy experiencein foreign countries at the present stage.Showing the main national trends, international hospital pharmacy and the functions of the Hospital (the hospital) pharmacists.

Resume. A gradual change in the structure of cardiomyocytes during the intraperitoneal administration of a pure culture of Streptococcus pneumoniae, up to pronounced vasodilatation, edema of the stroma, fragmentation of cardiomyocytes, cardiomyocyte hypertrophy, and interstitial myocarditis with proliferation of connective tissue are observed.

Summary. The purpose of the study: early detection of moderately increased albuminuria and analysis of the functional state of the kidneys in chronic obstructive pulmonary disease in conditions of lowlands.
Material and methods: 82 patients with COPD of varying severity and healthy people were examined. The average age was 60,53+15.48. All patients underwent determination of moderately increased albuminuria, assessment of respiratory function and indicators of renal function.
Results: There is an early and significant change in indicators of kidney function that correlate with the degree of bronchial obstruction in COPD patients.

Resume. In this work we have studied the dynamics of morbidity of the most common causes of chronic kidney disease in The Kyrgyz Republic for the period between 2009-2015 years. We revealed the pronounced upsurge of diabetes mellitus and arterial hypertension. The dynamics of morbidity in nephrotic syndrome, acute and chronic glomerulonephritis showed a tendency to rise.

The resume. To study the prevalence of diabetes in the Issyk-Kul and Naryn regions, to develop reliable information. The metod of one-stage area sample surveyed. The sample of a random 1647 inhabitants of the Issyk-Kul and Naryn region 603. Thefasting glucoselevels and 2 hours after a meal was checking byblood glucose monitor. Glucose levels were determined in patients aged 45 years and older, with hypertension, BMIabove 25 kg/m2. The diagnosis of diabetes was established at the criteria’s of WHO (1999, 2003). The prevalence of diabetes in the Issyk-Kul and Naryn regions exceeds official information. During and active detection of diabetes prevent the development of complications, mortality and disability from it.

Summary. To study the development of diabetic neuropathy (DN) in patients with diabetes mellitus (DM), depending on risk factors (RF) 166 diabetic patients were examined with second type of diabetes mellitus (DM2). In order to identify the severity of diabetic neuropathy, wefocused on clinical data and quantitative tests.Diabetic neuropathy occurs in 92.2% of patients. Quantitative assessment of the severity of diabetic neuropathy, wasdetermined by calculating the scale of neurosymptomatic accounts, reflecting mainly a subjective assessment, and this was brighter represented in women, and in neurodysfunctional account as a reflective tool assessment, in contrast was more expressed in males. The risk factors, such as hypertension and sex (male),have big affectonthe severity of diabetic neuropathy. Duration of diabetes, have affectsonthe severity of diabetic neuropathy on a scale of neuro symptomatic account, for a women.

Summary: The article presents the clinical and epidemiological characteristics of tick-borne rickettsiosis from RCIH reports for years 2011-2016 that proves the existence of dangerous places (full of ticks) across the country and high risk of catching disease among young people spending time in mountains from march to august. The main signs of tick-borne rickettsiosisare: primary affect, exanthema, regional lymphadenitis. Introduction of modern methods of laboratory diagnosis can improve practices of epidemiologic supervision on tick-borne infections in the country.

Resume: The use of non-medicated rehabilitation is a necessary aspect of the system of comprehensive rehabilitation of athletes and restore their health. By using these methods is provided: an easier passage of an athlete all stages of physical rehabilitation that improves the well-being, health, work, in the end, to achieve the best results in the competition;the use of methods of purification of the gastrointestinal tract, urogenital system, skin, lungs, improves physical performance; to use of these techniques does not cause side effects. Steam baths, saunas, aromatherapy, herbal medicine, salt and diet it is best approach for non-drug rehabilitation;the formation of the athletes adequate perception of rehabilitation measures. Further research is expected to take place in the direction of studying other athletes rehabilitate problem non-medicatedmethods.

Resume: This article presents the data of the pathogenetic approach to the treatment of Guillain – Barre syndrome in conditions of intensive care department. The clinical effects of plasmapharesis and immunoglobulin G on the example of clinical observations of patients with this neurological disorders passed through the intensive care unit are given.

Summary: In the article the case of the forensic expert practice, lead legislative frameworns for healing activities, legai issues and risk in the implementation of border healing. Warned criminal liability for ersonalinjuru or dead at the risk of exceeding the boundaries of healing is carried out data forensics.

Abstract: On the basis of the results of diagnostics and treatment of acute appendicitis by 136 pregnant women there were identified some characteristics of the course of acute surgical diseases during pregnancy. The use of modern diagnostic algorithm by assumption of the acute appendicitis by pregnant women improves the quality of diagnosis and reduce the number of diagnostic mistakes.

Resume: the article presents an analysis of 955 operations of patients with surgical pathology of the biliary tract in the period from 2015 to 2016. There were 167 men and 788 women .At the age of 25 to 82 years. The aim was to improve the results of treatment of patients with cholelithiasis (gall stones) through the introduction of the three-port method laparoscopic cholecystectomy (LCE). Complications were observed in 8 cases, the conversion in 7,deaths were not. LCE from three ports with safety and convenience is not lower than the conventional 4-port, despite the fact that the cosmetic result is much higher, and pain somewhat lower.

Summary: The results of surgical treatment of gallstone disease in young patients with laparotomy (128 pers.) and laparoscopic cholecystectomy (115 pers.) are presented. In the first group complications occurred in 6 (4.7%) and in the second in 2 (1.7%). At the moment of discharge all the complications were healed. The average hospital stay in the first group was 5,1 ± 0,31 bed-days, and the second 3,2 ± 0,17. Deaths were not.

Summary: analyzed diagnostic experience of 147 patients with obstructive jaundice. Obstructive jaundice of benign origin was observed in 71.4%, malignantin 28.6% of patients. Presented spectrum of the most important modern laboratory tests, as well as the most rational radiological methods to recognize the causes of jaundice.

Summary: 54 were observed in patients with pancreatic pseudocysts, 43 holds the traditional surgery, in 31 of 43 tsistogastroanastomoz applied in 4 tsistoeyunoanastomoz with outer nasogastric drainage, and 8 show only the external pseudocyst drainage. Complication occurred in 6 patients (11.1%), (residual cavity-1 tsistodigistivny reflux-1-one relapse, inflammation of the nasal passages and the oropharyngeal-3) and 11 patients fulfilled by external drainage improved our procedure in combination with momentary dual internal, complications were not observed.

Summary: The results of applying of Dimexidum preparation for decontamination in liver echinococcosis are given. In vitro-studies showed that at 3 minutes exposure scolexes die in 100%. Clinical use has shown that the drug penetrates into the capsule of hydatid cysts and pericapsular liver tissue.

Resume. The article presents the results of surgical treatment in patients with trigeminal neuralgia, conducted at the Clinic of Neurosurgery Hospital natsional MOH.

Резюме. На основании анализа результатов обследования 8 больных установлены оптимальные методы диагностики и лечения назальной ликвореи. Лечение этого заболевания хирургическое. Осуществляют послойную пластику ликворного свища гемостатической губкой “Тахокомб”, мышцей и сульфакрилатом.

Summary. The results of treatment of 150 patients with severe craniocerebral trauma are traced, drug methods for the prevention and treatment of acute gastric damage syndrome were included in the complex of intensive therapy in 34 (47.2%) cases. In the diagnostic algorithm, in addition to X-ray, computer tomography and magnetic resonance imaging, fibro-gastroduodenoscopy with a biopsy of the gastroduodenal mucosa was studied
to detect AGDS and the content of LPO products in biopsies of the gastric mucosa was examined.
It was found that erosive and ulcerative changes with multiple lesions in the control group were 61%, with single lesions 39%, while in the main group 2% and 5%, respectively.

Summary. In the article results of complex treatment of 120 patients with a craniocerebral trauma are presented. In 30.8% of patients with severe (n = 19) and moderate (n = 18) severity of ССТ, nutritional support was performed by the formation of percutaneous endoscopic gastrostomy. The imposition of gastrostomy is one of the main ways to provide enteral nutrition, when there is no possibility of installing a nasogastric tube. Complications were noted in 14 patients: aspiration in 6, gastrointestinal bleeding due to damage to the wall vessels or trauma of the gastric mucosa in 7, infection of the gastrostoma area was observed in 1.

Summary: In this work clinical study of Nazoferon drug (nasal drops) was done. There were two groups, consisting of 80 children aged from 1 month to 6 years with a clinical diagnosis of acute respiratory viral infections (ARI). The children were with severe form of disease and they were treated at the Republic clinical infectious hospital. Of these, 40 patients treated with Nazoferon, this main group, the other 40 patients whodid not receive the drug were in the control group. According to severity of 47.5% of patients in the control group were treated in the intensive care unit. The superinfection was in 40.0% of patients from the control group. The duration of fever was 1,4 ± 0,3; 4,2 ± 1,0 days. Length of hospital stay was 3,0 ± 0,1; 5,2 ± 1,0 days. The duration of antibiotic therapy was 3,0 ± 1,0; 9,8 ± 3,0 days and the duration of infusion therapy was 1,4 ± 0,3;. 4,2 ± 1,0 days. The difference in these groups has been identified (P <0,05). 

Summary: the article provides analysis of data obtained in the survey 47 patients with acute bacterial meningitis (ABM) at the age of 10 to 19 years. It was found that during periods of recovery incidence greater risk prone adolescents older age groups (40.4%). There is low etiological decoding of ABM in adolescents (80,8%). Predisposing factor for the development of ABM are transferred purulent-septic diseases of LOR organs, other neuroinfections and traumatic brain injury. ABM in adolescentsoccur in the severe form with the development of emergency conditions: cerebral edema (44.7%), septic shock (6.3%) and every third patient developed DIC.

Summary: The analysis of medical reports of children which received treatment in Republican clinical infectious hospital, for the period 2013-2016 years. All patients had heavy form acute intestinal diseases, with development of complication acutekidney insufficiency. Under vital indications, in 66,7% of cases patients were transferred in a department of nephrology for realization of an emergency dialysis.

Resume. The article considers principles of teaching foreign words to medical students. First of all, these are: principle of accessibility, principle of from known to unknown, from basic to complex. Analysis of the evolu-tionary processes in the grammar at the synchronic shearing indicates relation with variation, characterized with intra linguistical factors - realization of the law on systematicity, realization of principles of analogy, economy and tradition.

ЛЕЧЕБНЫЙ ПЛАЗМАФЕРЕЗ

К 105-ЛЕТИЮ СО ДНЯ РОЖДЕНИЯ ТИЛИСА АБРАМА ЮЛЬЕВИЧА

Тилис А.Ю. (1912-1989)