Vol. 3 No. 3 (2019): VESTNIK of KSMA

Summary. Morphological and anatomical study of the aboveground part of Lepidium latifolium L. which collected on the territory of Enbekshinsky district of Almaty region Republic of Kazakhstan was carried out. Anatomical study of the plant was carried-out according to the methodical manual Barykina R. P. For preparation of section were used dried raw materials. Fixation was carried out by the method of Strasbourg-Fleming (ethanol, glycerol, water, in a ratio of 1:1:1). Morphological and anatomical peculiarities of the stem and leaves of Lepidium latifolium L. were determined for identify this species.

Summary. The article presents the results of a study of acute and subacute toxicity of coated tablets on the basis of Alhagi spike extract on outbred white mice. It is shown that this drug does not have a toxic effect after a single (acute toxicity) and multiple (subacute toxicity, 30 days) oral administration.

An analysis of the range of anti-ulcer drugs registered in the Republic of Uzbekistan showed that anti-ulcer drugs on the pharmaceutical market of Uzbekistan are represented by such dosage forms as capsules, tablets, suspensions, injection solutions and granules, the vast ma­jority of which are preparations of synthetic origin. Considering that the share of anti-ulcer drugs registered in the Republic of Uzbekistan on the basis of medicinal plant materials is insignificant: 1 drug (3.34% of the number of domestic production), it is advisable to create an anti-ulcer drug based on medicinal plant materials.

Summary. A comparative analysis of the occurrence and prevalence of echinococcosis and alveococcosis in the Republic and in Endemic regions of Naryn and Osh arrears at time be­ tween 2009 and 2018 years. Found that residence of the Naryn region at an in tense the in­dicator was more likely suffers from echinococcosis, while the population of Osh area often suffered from alveococcosis.

Resume. With a view to explore features and characteristics of preschool aged children s diet, nutrition effect on physical development of children, 300 parents were interviewed, al­so taken up within the study had been taken anthropometric measurements of preschool aged children, who are residents of Ak-Orgo district. The lack of nutrition of preschool aged children had been revealed, which was expressed in a form of disbalanced malnutrition, lack of fruits, milk, diaries, fish and meat. Physical development indicators between organized amd disorganized children s compara­ tive analysis revealed that weight-to-height ratio of organized children is higher, than disor­ganized ones. The research showed the value of informing health workers at the family medicine center and preschool institutions about children s diet issues, also they must inter­view their parents about revealed disbalanced malnutrition issues.

Summary. The analysis of the epidemiological situation of measles in the Kyrgyz Republic was carried out. Unvaccinated children aged from one to five years are more often ill. The trend towards a decrease in measles immunization coverage, a decrease in the registration of measles cases in the regions of the Republic, which contributes to the lengthening of the epidemic process and the negative impact on the likelihood of measles vims elimination, continues. 

Summary. Objective: To study the effectiveness of the use of thioctic acid (ТА) on subjec­tive and objective indicators of the severity of distal diabetic polyneuropathy (DPN) de­pending on the duration of the disease in complex treatment in patients with type 2 diabetes mellitus (DM 2): 42 patients with type 2 diabetes in the main group, who treated with ТА (Tiocton) of Rompharm Company and 24 patients in the control group, who did not treat with ТА. Duration of DM 2: the 1st group from 5 to 10 years and the 2nd group over 10 years. The use of ТА in patients with type 2 diabetes with DPN has a positive effect in the form of a reduction in the severity of subjective and objective signs, more in group with du­ration of DM 2 over 10 years and in the control group a slight decrease only subjective signs. To obtain the stability of the positive effect of subjective and objective signs of DPN in DM 2 from the use of preparations of ТА for more than 1 month, it is necessary to con­tinue the use of ТА on an outpatient basis.

Summary. Toxoplasmosis is one of the actual opportunistic infections in HIV infected. Cerebral toxoplasmosis has no specific symptoms therefore it is difficult to diagnose. This article shows the clinical course of cerebral toxoplasmosis with HIV infection. Detection of antibodies by enzyme immunoassay and magnetic-resonance imaging are important in the laboratory diagnosis of cerebral toxoplasmosis.

Summary. In Kyrgyz Republic, the prevalence of viral hepatitis В and С are remain high, despite of the incidence over the past 5 years. Medical students of the 1st and 2nd years of pre-clinical education have insufficient level of knowledge about viral hepatitis. Low awareness on some risk factors of viral hepatitis, on ways of transmission and measures of prevention of chronic viral hepatitis, observance of a healthy lifestyle is revealed, on what it is necessary to pay more attention at preparation of future experts.

Resume. The article analyzes the features of the clinical picture and methods for diagnosing bleeding from esophageal varicose veins in patients with decompensated hepar cirrhosis. Mortality in this category of patients is associated with episodes of bleeding from esophage­ al and varicose veins and other more sites. In this regard, the use of existing and develop­ment of new, more effective methods for the prevention and treatment of bleeding from var­icose veins, developing as a result of the formation of portocaval anastomoses, is the key to improving the results of therapy in this category patients.

Summary. In our scientific work, a new method of combined elongation of large tubular bones is presented, based on the use of an external fixation device and plate osteosynthesis. The use of the proposed method of combined lengthening improves the immediate and long-term results in patients with congenital and acquired shortenings of limbs.

Summary. A comparative evaluation of the results of mitral valve (MV) prosthetics with the preservation of the posterior cusp and with the complete removal of the mitral valve flaps is given. 46 patients with mitral heart disease were analyzed. The main group consisted of 23 patients who underwent mitral valve replacement while maintaining the posterior cusps. The control group included 23 patients who underwent mitral valve implantation with complete removal of valves and chordal papillary apparatus. In the near postoperative period, the end-diastolic volume of the left ventricle in patients in the main group significantly decreased (by 8.9 ml compared to the initial preoperative parameters) than in patients in the control group (by 5.6 ml compared to the initial preoperative parameters). The increase in volume loads in patients of the control group was accompanied by a decrease in the ejection fraction due to remodeling of the left ventricular cavity. In patients of the main group, echocardiographic (EchoCG) data after surgery indicate the normalization of intracardiac hemodynamics, a decrease in linear and volumetric parameters of the left ventricle of the heart, as well as an increase in its contractility. In the control group slightly improved Echocardiographic indices of the left ventricle, but the fraction of the expulsion of the left ventricle decreased (from 59,0±9,8% to 56.1±9.4 per cent). In addition, the duration of cardiopulmonary bypass in the study group was shorter than in the control group (83.6±32.3 min 115.4±32.0 respectively).

Summary. The use of individually manufactured titanium implants with using the computer simulation method allows cranioplasty to be performed on patients with extensive and complex configuration defects. A number of indicators obtained in our work, such as reducing the time of the operation, achieving a good aesthetic and functional result, the absence of purulent-septic complications can already be used as an argument in favor of cranioplastics using individual titanium plates. By functional result, we understand the combination of neurological symptoms and subjective complaints. In our study, no case of deterioration of the patient's neurological status was recorded.

Retrospective analysis of 140 cases (male-82, female-58) with hypertensive intracerebral hemorrhage underwent surgical management was presented. Differentiated approach for surgical management of non-traumatic supratentorial intracerebral bleeding in absence of contraindications means punction method of removal for lateral and miscellaneous hematomas, and an open method for lobar hematomas using osteoplastic craniotomy allowing enough view of operative field with obligatory dura mater tight closing.  

Summary. This article presents comparative literature data on intervention techniques, epidemiology, indications, optimal timing and methods for tracheostomy, since in our country at present most tracheostomies are performed according to open surgical techniques, despite the fact that in developed countries preference is given to percutaneous dilatation tracheostomy technique.

Summary. A retrospective analysis of case histories of 58 children with infectious mononucleosis who were hospitalized in the Republican Clinical Infectious Diseases Hospital (RCIB) for 2017-2018 was carried out. The features of the clinical course of infectious mononucleosis were revealed.

Summary. This article presents a retrospective analysis of 76 stories birth of women with macrosomia delivery operational by the CPC Bishkek. Spend a literary analysis, studied the frequency of macrosomia, predisposing factors for the development of a macrosomia, choice of method of delivery during pregnancy and in childbirth with a big fetus.

Resume. The article presents the results of the detection of dystopic teeth of the upper and lower jaw in the study of 851 orthopantomography, presented by State Dental Clinic No. 3, State Dental Clinic No. 5, Dental Educational Scientific and Clinical Base KRSU. It was revealed that the dystopia of the canines of the upper jaw 13 teeth 0.351± 0.016, 23-0.308 ± 0.01 and the teeth of the lower jaw wisdom 38 teeth 0.263 ± 0.01, 48- 0.274 ± 0.01 is most common.

Summary. In this article, a dental aesthetic index (DAI) and the degree of need for orthodontic treatment of 272 children on diagnostic models of the jaws, which addressed the orthodontics department of children's dentistry of KSMA n.a. I.K. Akhunbaev was carried. It was revealed that 76% of children need compulsory treatment, and the most common bite pathology is crowded teeth in the incisal segments - 80.88 ± 1.46%

Summary. This article highlights the main issues of dentistry, namely, maxillofacial sur-gery, related to injuries of the maxillofacial area. The authors propose an adjustment of treatment taking into account the causal relationship at various levels of medical care in a unified system of rehabilitation of patients with maxillofacial area traumas.

Summary. The Constitution of the Kyrgyz Republic (Article 47) establishes the rights of everyone to health care and the obligation of the state to create conditions for medical care. This also concerns the quality of accessibility of medical care for penitentiary institutions population. The availability and quality of medical services were investigated in the female corrective colony №2. It was established that there are no elementary painkillers, antibiotics, medical gloves for gynecological examinations (convicted women buy themselves), dental care.
It is recommended: to intensify the participation of the authorized body in the field of health in health care in places of detention and transfer to it responsibility for the provision of medical care in penitentiary institutions.