ВЛИЯНИЕ ЭМПАГЛИФЛОЗИНА НА ЭФФЕКТИВНОСТЬ ЛЕЧЕНИЯ БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА В СОЧЕТАНИИ С СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ В ЗАВИСИМОСТИ ОТ УРОВНЯ АТФ (ОБЗОР ЛИТЕРАТУРЫ)
DOI:
https://doi.org/10.54890/.v2i2.1330Аннотация
Наряду с прогрессивным роста числа больных сахарным диабетом число лиц с хорошим гликемическим контролем остается низким, в связи с чем риски развития сердечно-сосудистых осложнений, в том числе сердечной недостаточности, достаточно высоки. Среди новых технологий снижения уровны глюкозы и рисков сердечной недостаточности изучен препарат из группы натрий-глюкозного котранспортера 2 типа – эмпаглифлозин, который фокусируется на воздействие молекулярных мишеней: за счет увеличения образования аденозинтрифосфата в результате окисления кетоновых тел, тем самым повышая сердечную эффективность. В данной статье нами проведен обзор современной научной обоснованной литературы с целью анализа влияния эмпаглифлозина на эффективность лечения больных сахарным диабетом 2 типа в сочетании с сердечной недостаточностью в зависимости от уровня АТФ.
Ключевые слова:
сахарный диабет 2 типа, сердечная недостаточность, ингибиторы натрий-глюкозного котранспортера-2, эмпаглифлозин, аденозинтрифосфат.Библиографические ссылки
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