ВЛИЯНИЕ ЭМПАГЛИФЛОЗИНА НА ЭФФЕКТИВНОСТЬ ЛЕЧЕНИЯ  БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА В СОЧЕТАНИИ  С СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ В ЗАВИСИМОСТИ ОТ УРОВНЯ АТФ (ОБЗОР ЛИТЕРАТУРЫ)

M.S. Moldobaeva; U.K. Omurzakova

doi:10.54890/.v2i2.1330

M.S. Moldobaeva U.K. Omurzakova

DOI:

https://doi.org/10.54890/.v2i2.1330

Abstract

Along with the progressive increase number of patients with diabetes mellitus, the number of people with good glycemic control remains low, and therefore the risks of cardiovascular complications, including heart failure, are quite high. Among the new technologies to reduce glucose levels and risks of heart failure we studied a drug from the group of sodium-glucose cotransporter type 2 - empagliflozin, which focuses on new molecular targets: by improving the formation of adenosine triphosphate as a result of oxidation of ketone bodies, improving cardiac efficiency. In this article, we reviewed the existing science-based literature to analyze the effect of empagliflozin on treatment efficacy in patients with type 2 diabetes mellitus combined with heart failure, depending on ATP levels.

Keywords:

type 2 diabetes mellitus, heart failure, sodium-glucose co-transporter-2 inhibitors, empagliflozin, adenosine triphosphate.

Author Biographies

M.S. Moldobaeva, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Internal diseases propedeutics with endocrinology and profpathology courses

U.K. Omurzakova, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Internal diseases propedeutics with endocrinology and profpathology courses

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