Vol. 4 No. 4 (2014): VESTNIK of KSMA

In this report we present the results of a retrospective study of 149 cases of obstetric hemorrhage, with which it was traditional hysterectomy as primary surgical method to stop bleeding. By the end, we were divided into two subgroups - the survivors (98) and deaths (51) cases. Compared groups of patients were not statistically different in age, mode of delivery, obstetric and somatic anamnesis. In the end, death was observed in 34.2%. It should be noted that 72.6% of deaths occurred in the regional medical - preventive institutions.

Aim of the study was to evaluate the physical development of adolescent girls – residents of Bishkek. Data from 390 high school students in the age of 15,5+0,4 were collected to examine. Majority of examined adolescent girls have average height/age and weight/age indicators for their age (M±1σ). 9,9% of the girls have weight deficit, height deficit was identified in 12,4% of examined girls.

Results of research concerning social and psychological adaptation, predilection to sacrifice and the relations to life in persons with different type of brain lateralization are presented. Two options of adaptation in persons with dextrocerebral asymmetry are revealed: the expressed sacrifice and desadaptation; adaptation without sacrificial attitudes.

In this article it is given sanitary - hygienic estimation of light exposure on educational audiences of KGMA and its influence on a functional condition of vision organ of students.

All dates indicate that the parasitic diseases reach high level in our Republic. It is jointed with agriculture and the poor level of personal hygiene of population. The children are amenable for those diseases, mostly. The deficiency of staff in parasitological works, remain as big problem.

This work investigated the prevalence of cytomegalovirus infection in the Osh Region. There were positive findings among patients studied (6067), 4091 patients were IgG positive (67.4%), and 1976 were IgG negative (32.6%). Chronic cytomegalovirus infection was found in children (27.2%) and in adult patients (72.8%). Specific G class immunoglobulins were the most frequent marker that was detected in patients tested for cytomegalovirus infection.

Described the clinical features of acute respiratory viral infections in children with hypoxic ischemic encephalopathy in 36 children aged from 1 month to yaer

The prevalence of health risk factors among students KSMA, KRSU.The sample included 837 university students from health sciences undergraduate. Mean age 21,3±1,5years. Students filled out a questionnaire to determine health risk factors. The study showed that medical students Kyrgyz universities, practicing unhealthy lifestyle.

In this work we studied cytokine concentrations of: Interleukin-1β (IL-1β), Interleukin-2 (IL-2), Interleukin-6 (IL-6), tumor necrosis factor (TNF), - confirming autoimmune origin of hemorrhagic vasculitis with violation activity of natural killer cells and cytotoxic lymphocytes. The obtained results show the effectiveness of the treatment of the therapy.

Research of 395 2-year-old children, inhabitants of Bishkek, full-term, with signs of intrauterine growth retardation (IUGR) at a birth is carried out – 257 children with hypotrophic variant and 138 children with hypoplastic variant. It is defined, that in investigated groups there is the raised infectious case rate and the metabolism disorders are registered and its frequency accrues with increase in degree of expressiveness of IUGR variants. The greatest infectious case rate is revealed in children with hypoplastic variant of IUGR.

This review focuses on the analysis of features of the treatment of acute coronary syndrome in patients with renal dysfunction.

The purpose of research is the study of amlodipine and lisinopril (еquator, Gedeon Richter, Austria) on circadian blood pressure monitoring (ABPM), echocardiography in patients with essential hypertension (EH). The study included 47 patients with EH II and III degree are at a dispensary in FMC №7 in Bishkek. On the background of a three-month course at a dose of 10 mg of the equator in the day according to ABPM, a significant decrease in both systolic and diastolic blood pressure. Reception equator reduced hemodynamic load on the left atrium.

A comparative assessment of the effectiveness of antihelikobakterna treatment of children with gastroduodenal ulcer using antisecretory drugs from the group of proton pump inhibitors from different generations. First in terms of our clinic applied parenteral administration of pantoprazole to children, reducing the healing time of the ulcer and inflammatory activity.

An assessment of ultrasound examinations of 68 patients with post-traumatic origin orchiepididymitis.

To assess the relationship between the decline in left ventricular systolic function in clinical and end-stage renal failure were examined 84 patients with chronic kidney disease (CKD). Found that patients with stage V CKD left ventricular sizes were significantly less than in patients with stage III-IV CKD, which was also accompanied by more expressed systolic dysfunction.

The purpose of the research in the study of the causes and structures of severe preeclampsia. Retrospective analysis of medical records of 104 women admittedt to the emergency department in 2011 was performed. From diagnosis: severe preeclampsia. To assess the effectiveness of the protocols used indicators.

In worker is presented multisegmental endoprosthesis replacement of large joints at 19 patients at diseases of rheumatoid polyarthritis and illness Bekhterev’s with 2010-on 2013. Age range makes from 18 to 64 years. The results remote are studied on SOI-3.

To assess the relationship between the decline in systolic function of the left ventricle (LV) in patients with myocardial infarction (MI) with ST-elevation (STEMI) and myocardial infarction without ST-elevation (NSTEMI) 97 patients were examined. It was found that in patients with STEMI the ejection fraction of the LV was significantly lower than in patients with NSTEMI, which was also accompanied by a more expressed LV systolic dysfunction.

Findings of peripheral blood and condition of marrowy blood formation of rat- males of the line Vistar from transplantable carcinosarcoma Walker-256 were investigated. Suspension of cages of transplantable carcinosarkoma Walker-256 entered into a hip muscle in a dose . For receiving serum of blood of rats it was made decapiting under a radio anesthesia for the 6th, 9th, 13th, 20th, 28th days of experiment from the moment of a tumor transplanting . For an assessment of indicators calculations of indicators of peripheral blood of rats were made. On all terms it was observed progressive decrease in quantity of erythrocytes and cells of marrow

The objective of this reseach has been the study of immunotropic properties of the cryopreserved pig substrate (CPSS) in guinea pig in the experimental pathology, such as a contact dermatitis guinea pigs. The guinea pigs had a normal immune status. It has been defined, that prophylactic administration of CPSS to animals stimulates the phagocytic function of lymphocytes, has no effect on antibody response and inhibits the growth of DTH reaction. In terms of allergic dermatitis CPSS decreases the severity of inflammation and normalizes the level of immunoglobulins. These results indicate immunomodulatory properties of CPSS and make it appropriate for further study to create antiallergic agent for highly pathogenic therapy of allergic dermatitis.

The term “orphan disease” (rare diseases, Eng. Orphan disease) first appeared in January 1983 in the United States in making the law «Orphan Drug Act», designed to encourage pharmaceutical companies to develop drugs for diseases that have a small market. According to this law, companies that develop these drugs can sell them without competition for seven years and have tax credits for clinical trials. There is no single, widely accepted definition of orphan diseases. There is no single level of disease prevalence in the population, in which it considered a rare start.