КЫРГЫЗ ЭТНИКАЛЫК ТОПТОГУ Β3- АДРЕНОРЕЦЕПТОРЛОР ГЕНИНИН TRP64ARG ПОЛИМОРФИЗИМИ АТЕРОГЕНДҮҮ ДИСЛИПИДЕМИЯ МЕНЕН АССОЦИАЦИЯСЫ
Аннотация
этникалык кыргыздардын тобунда ADRB3 генинин Arg64 аллел ЖТЛП-ХС төмөнкү деңгээли менен байланыш.
Ключові слова:
β3–адренорецепторлор, Trp64Arg полиморфизми, липиддик спектри, атерогендүү дислипидемиясы.Посилання
1. Bouchard C., Trembly A., Despres J.P., et al. The response to long-term overfeeding in identical twins. N Eng J Med. 1990; 322: 1477-1482.
2. Carmelli D., Cardon L.R., Fabsitz R. Clustering of hypertension, diabetes, and obesity in adult male twins: same genes or same environments. Am J Hum Genet 1994; 55:566-573.
3. Strosberg A.D. Association of β3-adrenoceptor polymorphism with obesity and diabetes: current status. Trends Pharmac Sci 1997; 18:449-45
4. Ursino M.G., Vasina V., Raschi E., et al. The b 3-adrenoceptor as a therapeutic target: current perspectives // Pharmacol Res. – 2009. – Vol. 59. – P.221–234.
5. Krief S., Strosberg A.D., Nyberg S., et al. Tissue distribution of В3-adrenergic receptor mRNA in man // J. Clin. Invest. - 1993. – Vol. 91. - P.344-349.
6. Lönnqvist F., Krief S., Strsberg A.D., et al. A pathogenic role of visceral fat b3-adrenoceptors in obesity // J. Clin. Invest. - 1995. - Vol. 95. - P.1109–1116.
7. Susulic V.S., Frederich R.C., Lawitts J., et al. Targeted disruption of the β3-adrenergic receptor gene. J Biol Chem 1995;270: 29483-29492.
8. Widen E., Lehto M., Kanninen T., et al. Association of a polymorphism in the β3-adrenergic receptor gene with features of the insulin resistance syndrome in Finns // N. Engl. J. Med. - 1995. - Vol. 333. - P.348-351.
9. Walston J., Silver K., Bogardus C., et al. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the b3-adrenergic-receptor-gene // N. Engl. J. Med. - 1995. - Vol. 333. - P.343–7.
10. Clement K., Vaisse C., Manning B., et al. Genetic variation in the b3-adrenergic-receptor and an increased capacity to gain weight in patients with morbid obesity. N Engl J Med 1995; 333:352-4.
11. Fujisawa T., Ikegami H., Yamato E. et al. Association of Trp64Arg mutation of the b3-adrenergic-receptor with type 2 diabetes and body weight gain // Diabetologia.-1996.- Vol.39. - P349-52.
12. Yoshida T., Sakane N., Umekawa T., et al. Mutation of b3-adrenergic-receptor gene and response to treatment of obesity. Lancet 1995; 346: 1433-1434.
13. Santos J.L., Perez-Bravo F., Martinez J.A., et al. No evidence for an association between genetic polymorphisms of beta(2)- and beta(3)-adrenergic-receptor genes with body mass index in Aymara natives from Chile. Nutrition 2002;18:255-258.
14.Hsueh W., Cole S., Shuldiner A., et al. Interactions between variants in the b3-adrenergic-receptor and peroxisome proliferator-activated receptor-y2 genes and obesity. Diabetes Care 2001; 24: 672-677.
15. Xinli W., Xiaomei T., Meihua P., Song L. Association of a mutation in the beta 3-adrenergic-receptor gene with obesity and response to dietary intervention in Chinese children. Acta Paediatr 2001;90: 1233-1237.
16. Ghosh S., Langefeld C.D., Ally D., et al. The W64R variant of the β3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. Diabetologia 1999; 42: 238-244.
17. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge // Clin. Chem. - 1972. - Vol. 18. - P.499-502.
18. Tonolo G., Melis M.G., Secchi G., et al. Association of Trp64Arg в3-Adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population // J. Hypertens. - 1999. - Vol. 17. - P.33-38.
19. Kadowaki H., Yasuda K., Iwamoto K., et al. A mutation in the b3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects // Biochem. Biophys. Res. Commun. - 1995. - Vol. 215. - P.555–560.
20.Hao K., Peng S., Xing H., et al. b3-Adrenergic receptor polymorphism and obesity-related phenotypes in hypertensive patients // Obesity. Res. - 2004. - Vol. 12. - P.1433–1434.
21. Oksanen L., Mustajoki P., Kaprio J., et al. Polymorphism of the beta 3-adrenergic receptor gene in morbid obesity // Int. J. Obes. Relat. Metab. Disord.- 1996.- Vol. 20.-P.1055-61.
