TENDENCY OF INCIDENCE WITH EPILEPSY IN KAZAKHSTAN

Z.A.  Bilalova; D.M.  Kulmirzaeva; Z.B.  Telmanova; Z.Z.  Kozhakhmetova; S.T.  Orozbaev; N.S.  Igisinov

doi:10.54890/.v5i5-6.434

Z.A. Bilalova D.M. Kulmirzaeva Z.B. Telmanova Z.Z. Kozhakhmetova S.T. Orozbaev N.S. Igisinov

DOI:

Аннотация

According to the WHO, epilepsy accounts for approximately 1% of the world’s total disease burden, and is fourth on the list of neuropsychiatric disorders, following depression, alcoholism, and cerebrovascular disease, with similar impact to the burden of breast and lung cancer. It affects over 70 million people worldwide and it's characterized by a lasting predisposition to generate spontaneous epileptic seizures and has numerous neurobiological, cognitive, and psychosocial consequences.
Aim. To study the trends of epilepsy incidence in Kazakhstan.
Material and methods: The research material was compiled summary reporting form number 12 of Ministry of Health of the Republic of Kazakhstan on new cases of epilepsy (ICD-10 – G40), established for the first time. A retrospective study was used as the main method for studying the incidence of epilepsy. According to generally accepted methods of biomedical statistics, extensive, intensive and equalized indicators of the incidence of epilepsy were calculated.
Results. For 2009-2018 78,429 new cases of epilepsy were registered in the republic, of which were in children – 47.6%, teenagers – 7.5% and adults –44.8%. The average annual incidence rate of epilepsy in the entire population of Kazakhstan was 45.6±3.0⁰/₀₀₀₀ (95% CI=39.7-51.4⁰/₀₀₀₀), and for population groups having been studied was: in children – 83.2±4.0⁰/₀₀₀₀ (95%CI=75.4-91.0⁰/₀₀₀₀), among teenagers – 84.6±6.5⁰/₀₀₀₀ (95% CI=71.9-97.3⁰/₀₀₀₀) and the adult population 29.3±2.6⁰/₀₀₀₀ (95% CI=24.3-34.3⁰/₀₀₀₀). The difference in incidence between groups was statistically significant. Disease tended to increase in all age groups: in children (Т=+5.7%), in adolescents (T=+9.8%) and in the adult population (Т=+9.8%).

Conclusion. According to the dynamics, epilepsy incidence in Kazakhstan has a increased tendency. The results obtained are recommended to be taken into account by health authorities when making managerial decisions.

Ключові слова:

epilepsy, morbidity, age characteristics, epidemiology, trends, Kazakhstan.

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