EPIDEMIOLOGY OF ACUTE EXOGENOUS POISONINGS  IN THE CHILDREN OF RYAZAN REGION

N.A. Belyh; N.A. Anikeeva; I.V. Piznur; E.V. Stezhkina; S.A. Nikonova; N.N. Fokicheva; M.N. Iyoshkina; G.A. Lebedinskaja

doi:10.54890/.v2i2.114

N.A. Belyh N.A. Anikeeva I.V. Piznur E.V. Stezhkina S.A. Nikonova N.N. Fokicheva M.N. Iyoshkina G.A. Lebedinskaja

DOI:

https://doi.org/10.54890/.v2i2.114

Аннотация

Aim. The study of the structure of acute poisoning in children in the Ryazan region during 2013–2017 years. Materials and Methods. A retrospective analysis of 548 cases of acute poisoning in children in Ryazan region for 2013-2017 years was performed. Results. Most often, poisoning occurred in toddlers (35.6%) and adolescents (45.1%). The structure of the etiological factors were medications (45.1%) and unspecified substances (33.6%), alcohol and its surrogates (14.6%). Poisonings with alcohol and smoking mixtures were recorded in adolescents, more often in boys. Poisonings by unspecified medicines were dominated among medicines intoxications (33.6%). Poisonings by nasal decongestants (17.8%), sedatives and hypnotics (13.3%), psychotropic (6.4%), hypotensive (6.8%), non-steroidal anti-inflammatory drugs (NSAIDs) (6.8%) were dominated among specified medicines. Two hundred thirty children had treatment in the department of pediatric resuscitation and intensive care. Poisonings were as a result of an accident in 60.3% cases, suicidal attempts – in 34.3%, overdose of psychotropic drugs in adolescents, who have been using these drugs for a long time (5.5%). Two patients were died as a result of poisoning by wild mushrooms (pale toadstool). Conclusions. In the structure of acute poisoning in children of the Ryazan region in 2013-2017 years the most common were intoxication with drugs, unspecified substances, alcohol and its surrogates. Most often, poisoning occurred in toddlers and adolescents. A decrease of rate of toddlers and an increase of adolescents were in dynamics. The rate of alcohol intoxications, mainly in teenagers, increased in 2.5 times.

Ключові слова:

acute exogenous poisoning, children, intoxication.

Посилання

1. Titidezh V, Arefi M, Taghaddosinejad F. Behnoush B, Pour SA, Mahboobi M. Epidemiologic profile of deaths due to drug and chemical poisoning in patients referred to Baharloo Hospital of Tehran, 2011 to 2014. J Forensic Leg Med. 2019;64:31-33. doi: 10.1016/j.jflm.2019.02.009. Epub 2019 Feb 1.

2. Azab SM, Hirshon JM, Hayes BD, El-Setouhy M, Smith GS, Sakr ML et al. Epidemiology of acute poisoning in children presenting to the poisoning treatment center at Ain Shams University in Cairo, Egypt, 2009-2013. ClinToxicol (Phila). 2016;54(1):20-6. doi: 10.3109/15563650.2015.1112014.

3. Abhulimhen-Iyoha BI, Israel-Aina YT. Pattern of Accidental Childhood Poisoning at the Children Emergency Room of the University of Benin Teaching Hospital, Benin City, Nigeria. West Afr J Med. 2018;35(2):85-89.

4. Баранов А.А., Багненко С.Ф., Намазова-Баранова Л.С., Александрович Ю.С., Пшениснов К.В., Алексеева Е. А. и др. Клинические рекомендации по оказанию скороʹ медицинскоʹ помощи при острых отравлениях у детеʹ. Педиатрическая фармакология. 2015;12(6):657-66. doi: 10.15690/pf.v12i6.1489 [Baranov AA, Bagnenko SF, Namazova-Baranova LS, Alexandrovich YuS, Pshenisnov KV, Alexeyeva EA et al. Clinical Recommendations on Emergency Medical Care Rendering to Children with Acute Intoxication. Pediatric pharmacology. 2015;12(6):657-66. (In Russ.).]

5. Землянова Е.В. Анализ статистики смертности детеʹ̆ от несчастных случаев, отравлениʹ и травм с 2000 г. по 2008 г. Социальные аспекты здоровья населения. 2009;12(4):6. [Zemlyanova EV. Analysis of statistics of mortality from accidents, poisonings and traumas in children. Social aspects of population health. 2009;12(4):6. (In Russ.).]

6. Лужников Е.А. Педиатрическая клиническая токсикология. Ростов н/Д.: Феникс; 2013. 253 с. [Luzhnikov EA. Pediatricheskaya klinicheskaya toksikologiya. Rostov n/D.: Feniks; 2013. 253 p. (In Russ.).]

7. Макарова И.В. Клиническая токсикология детеʹ и подростков. Москва: Медицина; 1999. 400 с. [Makarova IV. Klinicheskaya toksikologiya detey i podrostkov. Moskva: Meditsina; 1999. 400 p. (In Russ.).]

8. Alvarez-Pitti J, Rodrнguez-Varela A, Morales-Carpi C, Lurbe E, Estaс L. Naphazoline intoxication in children. Eur J Pediatr. 2006;165(11):815-6.

9. Павленко Т.Н., Головко О.В., Кацова Г.Б., Малеева Н.П. Динамика и структура острых отравлениʹ у детеʹ̆ г. Оренбурга. Теоретические и прикладные аспекты современноʹ̆ науки. 2014;5–2:67-72. [Pavlenko TN, Golovko OV, Kacova GB, Maleeva NP. Dinamika i struktura ostryh otravleniʬ u deteʬ g. Orenburga. Teoreticheskie i prikladnye aspekty sovremennŏj nauki. 2014;5–2:67-72. (In Russ.).]

10. Гладченко А.Ю., Сердюков А.Г., Гладченко Ю.Л. Острые химические отравления детеʹ Астраханскоʹ области медико-социальная проблема. Сибирское медицинское обозрение. 2010;1:57-60. [Gladchenco AYu, Serdyucov AG, Gladchenco YuL. Acute chemical intoxication in children from Astrakhan region – medical and social problem. Siberian Medical Review. 2010;1:57-60. (In Russ.).]

11. Белых Н.А. Йодныʹ дефицит и интеллект ребенка. Механизмы негативного влияния и пути профилактики. Наука молодых (Eruditio Juvenium). 2017;2:251-64. [Belykh NA. Iodine deficiency and neurodevelopment in infants: negative influence and methods of iodine prophylaxis. Science of the young (Eruditio Juvenium). 2017;2:251-64. (In Russ.).]

12. Дмитриева Н.В., Гудков Р.А. Динамика и тенденции детскоʹ заболеваемости в Рязанскоʹ области за 1990-99 годы. Рос. медико-биол. вестн. им. акад. И.П. Павлова. 2001;3-4:32-6. [Dmitrieva NV, Gudkov RA. Dinamika i tendencii detskoj zabolevaemosti v Ryazanskoj oblasti za 1990-99 gody. Ros. mediko-biol. vestn. im. akad. I.P. Pavlova. 2001;3-4:32-6. (In Russ.).].

13. Huang H, Li B, Chen Y, Yuan Y, Xiong P, Zhang W-D, Fu L-N et al. Etiology and risk factors for childhood unintentional injuries: a retrospective analysis of data at a pediatric intensive care unit. Zhongguo Dang Dai ErKeZaZhi. 2019;21(4):323-326. doi: 10.7499/j.issn.1008-8830.2019.04.004.

14. Disfani HF, Kamandi M., Mousavi SM, Sadrzadeh SM, Farzaneh R, Doolabi N et al. Risk factors contributing to the incidence and mortality of acute childhood poisoning in emergency department patients in Iran: a hospital-based casecontrol study. Epidemiol Health. 2019;41:e2019016. doi: 10.4178/epih.e2019016. Epub 2019 Apr 23.