COMPARATIVE CHARACTERISTICS OF SECRETARY DIARRHEA CAUSED BY ROTAVIRUS AND NOROVIRUS IN YOUNG CHILDREN

Abstract

The paper gives a comparative clinical and epidemiological characteristic of secretory diarrhea in 117 young children with rotavirus and norovirus infections who received treatment at the Republican Clinical Infectious Diseases Hospital in Bishkek for the period 2016- 2020. As a result of the study, it was found that secretory diarrhea caused by rotavirus is more often (58,1%) observed in children of the first year of life, especially at the age of 6 to 9 months. (36,0%). Whereas norovirus infection, significantly p<0.01 more often (61,3%) occurs among children aged 1 to 3 years, with an aggravated premorbid background (64,5%), including anemia (40,0%) and rickets (25,0%). Basically, children from the compared groups were admitted in the winter season (88,5%; 67,8%) and were residents of the city of Bishkek (60,5%; 67,7%), boys predominated among the patients (54,7%; 54,8%). The disease in the 2 compared groups began acutely with symptoms of gastroenteritis. Secretory diarrhea caused by rotavirus proceeded mainly in severe form (61,4%; 45,2%) with an unfavorable outcome in 4,0% of cases. In children with norovirus infection, significantly p<0.01 more often (38,6%; 51,6%), the disease proceeded in a moderate form. It should be noted that the symptoms of moderate dehydration (31,3%; 48,4%) were more often detected in children with norovirus infection (group 2). The diagnosis of rotavirus and norovirus infections was confirmed using an immunochromatographic rapid stool test. All children with norovirus infection and the vast majority (96,0%) of children with rotavirus infection were discharged from the hospital with improvement.