CHRONIC DISSEMINATED (GRANULEMATOUS) CANDIDIASIS: CLINICAL CASE OF LONG-TERM OBSERVATION
DOI:
https://doi.org/10.54890/.v5i5-6.374Abstract
Abstract: the article describes a rare clinical case of severe chronic granulomatous candidiasis in a child of fifteen years in dynamics, with the onset of the disease in infancy and late diagnosis at 6 years with lesions of the scalp, face, trunk, and brushes that accompanied the accompanying iron deficiency anemia and ascariasis. After 9 years from the moment of the first hospitalization, the patient experienced an aggravation of the process with a widespread lesion of the facial skin, breasts and was represented by plaques with massive crusts and scales on the surface. A good effect was obtained from complex treatment with fluconazole, vitamin preparations and local therapy with an «Eskaderm», 10% sulfur salicylic ointment.
Keywords:
chronic granulomatous candidiasis, ascariasis, iron deficiency anemia, fluconazole.References
1. Антоньев, А.А. Кандидоз кожи и слизистых оболочек / А.А. Антоньев, Л.А. Бульвахтер, Л.К. Глазкова. - М.: Медицина. -1985. – 16 с.
2. Herrod, H.G. Chronic mucocutaneous candidiasis in childhood and complications of non-Candida infection: a report of the Pediatric Immunodeficiency Collaborative Study Group // J Pediatr. - Mar 1990. - Vol. 116, № 3. - Р. 377-382.
3. Быков, В.Л. Патогенез и морфогенез кандидоза при иммунодепрессии // Архив патологии. – 1990. – Т. 52, №11. – С. 67-70.
4. Netea, M.G. Innate immune mechanisms for recognition and uptake of Candida species / M.G. Netea, L. Marodi // Trends Immunology. - 2010. - V. 31. - P. 346-353.
5. Балтабаев, М.К. Кандидоз кожи и слизистых оболочек: методические рекомендации / М.К. Балтабаев, М.Б. Усубалиев. – 2012. – 37 с.
6 Хронiчний шкiрно – слизовиий кандидоз як первинний iмунодефiцит у дiтей / Л.І. Чернишова, А.В. Бондаренко, А.П. Волоха и др. // Здоровье ребенка. – 2013. - №2. – С. 113
7. Harms, M. KID syndrome (keratitis, ich-thyosis, and deafness) and chronic muco-cutaneous candidiasis: case report and re-view of the literature / M.S. Gilardi, P.M. Levy // Pediatric Dermatology. - 1984. - Р. 1-7.
8. Lilic, D. New perspectives on the immu-nology of chronic mucocuta-neous candid-iasis // Curr. Opin. Infect. Dis. - 2002. Vol. 15, № 2. - P. 143-7.
9. Kirkpatrick, C.H. Chronic mucocutaneous candidiasis // Pediatr Infect Dis J. - 2001. - Vol. 20, №2. - Р. 197-206.