Current trends in surgical treatment of liver echinococcosis
Abstract
The choice of the optimal method of surgical treatment of hepatic echinococcosis continues to be a subject of debate in the surgical community. Despite the historical priority of organ-preserving approaches, radical methods of surgical intervention on the liver have been actively developed and introduced into clinical practice in recent years. The purpose of the study was to analyse the immediate and long-term results of the use of organ-preserving and radical surgical interventions in hepatic echinococcosis. 362 patients with hydatid echinococcosis of the liver were examined. Of these, 302 (75.8%) had primary echinococcosis and 60 (24.2%) had recurrent echinococcosis. There were 179 men (49.5%) and 183 women (50.5%). Conventional surgical procedures were performed in 232 (64.1%) patients with hepatic echinococcosis. With conventional echinococcectomy, postoperative mortality was 0.9%, postoperative complications developed in 47 patients, which was 20.3%, and disease recurrence was observed in 11 (4.7%) patients. The most frequently observed residual cavity after echinococcectomy was in 29 (12.4%) patients, including suppuration of the residual cavity in 10 (4.3%) patients. Radical surgical treatment of hepatic echinococcosis was performed in 130 patients, of whom 2 (1.5%) died. After radical surgery, specific complications were noted in 18 patients, which amounted to 13.8%. The most common complications were haemorrhagic and biliary complications, which were detected in 9 patients. Intra-abdominal bleeding occurred in 5 patients, of which 4 had less intense bleeding and was stopped after haemostatic therapy, and one patient underwent a relaparatomy and bleeding was stopped early after surgery. Liver failure developed in two patients who underwent liver resection and combined operations, which were corrected with drug treatment. Radical operations with removal of the fibrous capsule with all pericystic liver tissues (pericystectomy and resection) contribute to improving the immediate and long-term results of surgical treatment of echinococcosis
Keywords:
echinococcosis; antisepsis; echinococcectomy; resection; pericystectomy; relapse preventionReferences
[1] Aliev MZh, Kalybekov TA, Niyazbekov KI. The prevalence of echinococcosis and the reasons for its growth (literature review). Sci New Technol Innov Kyrg. 2021;2:32–7. DOI: 10.26104/NNTIK.2019.45
[2] Bebezov BKh, Bebezov HS, Umetaliev TM, Mamashev ND, Belekbaev TM, Surov EA, et al. Surgical treatment of liver alveococcosis. Ann HPB Surg. 2019:24(3):124–31. DOI: 10.16931/1995-5464.20193124-131
[3] Karimov ShI, Krotov NF, Kim VL, Berkinov UB. Problems and prospects of surgical treatment of patients with echinococcosis of the liver and lungs. Ann Surg Hepatol. 2008;13(1):56–60.
[4] Resolution of XXII international congress of surgeon-hepatologists of sis countries. 7–9 September 2015 (Tashkent, Uzbekistan). Ann HPB Surg. 2015;20(4):128–31.
[5] Musaev GKh, Fatyanova AS, Levkin VV. Principles and modern trends in liver echinococcosis treatment. Pirogov Russ J Surg. 2017;(12):90-94. DOI: 10.17116/hirurgia20171290-94
[6] Skipenko OG, Parshin VD, Shatverjan GA, Bejanjian AL, Rarnikova NP, Ganiev VD, et al. Liver echinococcosis: Current trends in surgical strategy. Ann Surg Hepatol. 2011;16(4):34–9.
[7] Aydin U, Yazici P, Onen Z. The optimal treatment of hydatid cyst of the liver: Radical surgery with a significant reduced risk of recurrence. Turk J Gastroenterol. 2008;19(1):33–9.
[8] Toirov AS, Mirkhodzhaev IA, Babazhanov AS. An innovative method for the treatment of residual cavities after echinococcectomy of the liver. Biol Integr Med. 2022:57(4):128–40.
[9] Mikhin IV, Kosivtsov OA, Ponomarev SV. Giant echinococcal cyst of the left lobe of the liver in a patient previously treated with echinococcectomy of the left lung. Clin Case Rep. 2014;3:52–6.
[10] Krasnov AO, Anishchenko VV, Krasnov KA, Pelts VA, Krasnov OA, Pavlenko VV. The current state of diagnostics and surgical treatment of liver echinococcosis (literature review). Acta Biomed Sci. 2022;7(1):171–81. DOI:10.29413/ABS.2022-7.1.20
[11] Seisembaev MA, Baimakhanov BB, Ramazanov ME, Sakhipov MM, Toxanbayev DS, Betirova DCH. Selection of the optimal method of surgical treatment of patients with liver echinococcosis. Bull Surg Kaz. 2008;4:13–6.
[12] Pavlyuk GV, Buzhor PV, Moraru VA. Echinococcosis of the liver: Pericystectomy or echinococcectomy. In: Current issues in hepatopancreatobiliary surgery: Proceedings of the 23rd international congress of the association of hepatopancreatobiliary surgeons of the CIS countries. Minsk: Association of Hepatopancreatobiliary Surgeons of the CIS Countries; 2016. 405–6.
[13] Makhmadov FI, Muminov BG, Kholov KR. Surgical treatment of large echinococcal cysts of the liver. Ann Surg Hepatol. 2007;12(3):14–7.
[14] Kurbonov KM, Azizzoda ZA, Efanov MG, Ruziboyzoda KR. Results of the application of minimally invasive technologies in the surgical treatment of liver echinococcosis and its complications. Avicenna Bull. 2020;22(3):446–52.
[15] Abdurakhmanov BA, Baimagambetov AK, Kaldygozova GE. Results of the application of endovideo-surgical interventions in the treatment of liver echinococcosis. Bull Kaz Nat Med Univ. 2020;1:270–2.
[16] Durleshter VM, Andreev AV, Kulakov AA, Tokarenko EV. Treatment of recurrent echinococcosis of the abdominal cavity, retroperitoneal space and mediastinum using percutaneous minimally invasive technologies. Ann Surg Hepatol. 2015;20(3):129–32. DOI: 10.16931/1995-5464.20153129-132
[17] Shabunin AV, Bedin VV, Tavobilov MM, Lebedev SS, Karpov AA, Lantsynova AV. Laparoscopic and robotic surgery: Pathways to improving liver echinococcosis perioperative results. Mosc Surg J. 2021;1:34–8. DOI: 10.17238/issn2072-3180.2021.1.34-38
[18] Musaev AI. Methods for eliminating the cavity of fibrous capsules. Bishkek: Uchkun; 1999. 156.
[19] Prudkov MI, Amonov ShSh, Orlov OG. Operations from a mini-access in the surgical treatment of liver echinococcosis. Ann Surg Hepatol. 2011;16(4):40–5.
[20] Wen H, Vuitton L, Tuxun T, Li J, Vuitton DA, Zhang W, et al. Echinococcosis: Advances in the 21st century. Clin Microbiol Rev. 2019;32(2):e00075-18. DOI: 10.1128/CMR.00075-18
[21] Odishelashvili LG, Zurnadzhiants VA, Odishelashvili GD, Pakhnov DV. The choice of the method of surgical treatment of residual cavities after echinococcectomy. Astrakhan Med J. 2020;15(2):6-12.

