APOPTOSIS PHENOMENON AND ITS CHARACTERISTICS AFTER EXPERIMENTAL AND CLINICAL TRAUMATIC HEAD INJURY
Abstract
Several neuronal populations are selectively vulnerable to cell death after traumatic brain injury (TBI) in experimental models and in man. Both necrotic and apoptotic cell death have been described after experimental and clinical TBI. A common feature apoptotic cell death were determined in the injured cortex at 6 rats in the acute posttraumatical period. The cortex ipsilateral and contralateral to the impact site exhibited apoptosis with varying staining intensities in 7 days after injury.
Keywords:
experimental traumatic brain injury, apoptosis, pathomorphology.References
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