«THYROID HORMONES ROLE IN ORGANISM ANTISTRESS-SYSTEM»
Abstract
In experiences on rats was show, that small thyroid hormones doses increase organism stability to antagonistic stressors influence - heat (t 42°C during 3 h) and cold (t 4-6°C during 3 h) of different complexity - isolated and combined with immobilization, because activate myocardial local stress-limited systems - heat shock proteins (HSP 70) and antioxidant (superoxiddismutase, catalase, whole antioxidant activity) in the result of their specific action on cell genetic apparatus. Obtained data prove the important role of thyroid hormones in organism antistress-system.
References
ЛИТЕРАТУРА
1. Баевский P.M., Берсенева А.П. Оценка адаптационных возможностей организма и риск развитий заболеваний. Медицина, М. 1997.
2. Дыгало Н.Н. Концепция «биологического» стресса (к 100-летию со дня рождения Ганса Сельё). Успехи физиод. наук. 38 (4): 100 - 102. 2007.
3. Jocko X. Liberation of thyreotropin, thyroxine and tri-iodthyronine in the controllable and uncontrollable stress and after administration of naloxone in rats. J. Physiol. Pharmacol. 47 (2): 303 -3 1 0 . 1996.
4. Pacak KL, Palkovits М., Yadid G. et al. Heterogeneous neurochemical responses to different stressors: a fest of Selye’s doctrine of soecificity. Amer. J. Physiol. 275 (4, at 2): R1247 —R1255.1998.
5. Крыжановский Г.Н. Введение в общую патофизиологию.- М.: РГМУ/2000.- 71 с.
