THE EFFECTIVENESS OF NEUROPROTECTION IN CHRONIC CEREBRAL ISCHEMIA COGNITIVE IMPAIRMENT TREATMENT

Abstract

neuropeptide cortexin has universal neurometabolic and neuroprotective action. Our investigation is devoted to the effectiveness of cortexin discircular encephalopathy. 54 patients were examinated, 30 patients are the main group and 24 control. The main group patients got cortexin and based therapy, patients of the control group got magnesium sulfate. The assissment of treatment results was carried out using clinical and neuropsychological study methods. On the background of cortexin therapy it was marked the improvement of subjective and objective data in many patients. In 90,3% of patients it was marked the decrease of subjective symptoms intensity: emotional lability, anxiety and depressive reactions, fatigability headache. Cortexin may be recommended as neuroprotector not only in cerebravascular deseases but in pathological conditions accompanied by impairment of cognitive brain functions

Keywords:

cortexin, neuropeptide, discircular encephalopathy.

Author Biographies

Z. Batool , I.K. Akhunbaev Kyrgyz State Medical Academy,

Neurology department with medicine genetics course

I.L. Lutsenko , I.K. Akhunbaev Kyrgyz State Medical Academy,

Neurology department with medicine genetics course

References

1. Adriani W., Granstrem O., Romano E. et al. Modulatory effects of cortexin and cortagen on locomotor activity and anxiety-related behavior in mice // Open Neuropsychopharmacology Journal. 2009. Vol. 2. P. 22–29.

2. Bowler J.V., Hachinski V. The concept of vascular cognitive impairment // In T. Erkinjuntti, S. Gauthier (eds). Vascular cognitive impairment. Martin Dunitz. – 2002.-P.9-26

3. Dyakonov A. M. Cortexin - preparation of the XXI century. Treatment and prevention of diseases of the brain / / Aqua Vitae. 2001. Number 3. P. 22-23

4. Granstrem O.K., Sorokina E.G. and etc. The latest news about cortexin (neuroprotection at the molecular level) / / Terra Medica Nova. 2008. Number 5. P. 1-4

Published

2024-11-28

How to Cite

Батул , З., and И. Луценко. “THE EFFECTIVENESS OF NEUROPROTECTION IN CHRONIC CEREBRAL ISCHEMIA COGNITIVE IMPAIRMENT TREATMENT”. Euroasian Health Journal, vol. 2, no. 2, Nov. 2024, pp. 75-76, https://vestnik.kgma.kg/index.php/vestnik/article/view/1924.

Issue

Section

ORIGINAL RESEARCH