ПРИМЕНЕНИЕ БОТУЛИНОТЕРАПИИ У ДЕТЕЙ ПРИ ЦЕРЕБРАЛЬНОМ ПАРАЛИЧЕ

E.Dzh. Dzhamalbekova; S.A. Dzhumabekov; K.T.  Sharshenov

doi:10.54890/1694-8882-2024-4-25

E.Dzh. Dzhamalbekova S.A. Dzhumabekov K.T. Sharshenov

DOI:

https://doi.org/10.54890/1694-8882-2024-4-25

Abstract

One of the new modern and evidence-based treatment methods in the world for cerebral palsy is botulinum therapy, which was first used in the Kyrgyz Republic on the basis of the Bishkek Research Center of Traumatology and Orthopedics in the Department of Pediatric Orthopedics in 2020. On this basis, we examined 69 children suffering from cerebral palsy who received a course of botulinum therapy in the period from 2021 to 2023. The scientific value of this work can become the basis for the further development of the botulinum toxin therapy method for children suffering from cerebral palsy, while significantly reducing orthopedic complications that often occur with this pathology, and also contribute to the development of science in the field of medicine in the country. After the use of botulinum toxin type A, changes in spasticity were assessed using the Ashworth and Motor Function Classification System scales; before and after therapy, a video and photo analysis of the patients’ range of motion was performed. As a result of the study and evaluation of the use of botulinum therapy, positive dynamics of indicators in the motor sphere were noted in children suffering from cerebral palsy.

Keywords:

cerebral palsy, botulinum therapy, Relatox

Author Biographies

E.Dzh. Dzhamalbekova, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Traumatology, Orthopedics and Extreme Surgery

S.A. Dzhumabekov, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Traumatology, Orthopedics and Extreme Surgery

K.T. Sharshenov , Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Traumatology, Orthopedics and Extreme Surgery

References

1. Клочкова О.А., Куренков А.Л. Ботулинотерапия при детском церебральном параличе: практические советы и ультразвуковой контроль. М.: МЕДпресс-информ; 2020. 248 с.

2. Клочкова О.А., Куренков А.Л. Выбор целей и приоритетов ботулинотерапии у пациентов с детским церебральным параличом. Журнал неврологи и психиатрии им. С.С. Корсакова. 2019;119(2):118-124. https://doi.org/ 10.17116/jnevro2019119021118

3. Змановская В.А., Левитина Е.В., Попков Д.А., Буторина М.Н., Павлова О.Л. Длительное применение препарата ботулинического токсина типа А: Диспорт в комплексной реабилитации детей со спастическими формами церебрального паралича. Журнал неврологии и психиатрии им. С.С. Корсакова. 2014;114(7):33-36.

4. Blair E, Langdon K, McIntyre S, Lawrence D, Watson L. Survival and mortality in cerebral palsy: observations to the sixth decade from a data linkage study of a total population register and National Death Index. BMC Neurol. 2019;19(1):111. Published 2019 Jun 4. doi:10.1186/s12883-019-1343-1

5. Baranello G, Signorini S, Tinelli F, Guzzetta A, Pagliano E, Rossi A, et al. Visual Function Classification System for children with cerebral palsy: development and validation [published correction appears in Dev Med Child Neurol. 2020 Mar;62(3):399. doi: 10.1111/dmcn.14464]. Dev Med Child Neurol. 2020;62(1):104-110. doi:10.1111/dmcn.14270

6. Palisano RJ, Rosenbaum P, Bartlett D, Livingston MH. Content validity of the expanded and revised Gross Motor Function Classification System. Dev Med Child Neurol. 2008;50(10):744-750. https://doi.org/10.1111/j.14698749 .2008.03089.x

7. Ashworth B. Preliminary trial of carisoprodol in multiple sclerosis. Practitioner. 1964;192:540–542.

8. Cernuda-Morollón E, Ramón C, Martínez-Camblor P, Serrano-Pertierra E, Larrosa D, Pascual J. OnabotulinumtoxinA decreases interictal CGRP plasma levels in patients with chronic migraine. Pain. 2015;156(5):820-824. https://doi.org/10.1097/j.pain.0000000000000119

9. Figueiredo EM, Ferreira GB, Maia Moreira RC, Kirkwood RN, Fetters L. Efficacy of ankle-foot orthoses on gait of children with cerebral palsy: systematic review of literature. Pediatr Phys Ther. 2008;20(3):207-223. https://doi.org/10.1097/PEP. 0b013e318181fb34

10. Koman LA, Li Z, Smith BP. Orthopaedic intervention in the management of cerebral palsy: botulinum toxins. In: Eliasson AC, Burtner P, eds. Improving hand function in children with cerebral palsy: theory, evidence and intervention. London: Mac Keith Press; 2008:35.

11. Thomason P, Rodda J, Willoughby K, Graham K. Orthopaedic assessment. In: Dan B, Mayston M, Paneth N, Rosenbloom L, eds. Cerebral palsy: science and clinical practice London: Mac Keith Press; 2014:1-10.