EARLY COMPLICATIONS AFTER COMBINED AND COMPLEX TREATMENT IN PATIENTS WITH STAGE II B CERVICAL CANCER

Abstract

Cervical cancer occupies one of the leading positions in the structure of malignant neoplasms of the reproductive system organs. Treatment of localized forms of cervical cancer gives good results in the 5-year overall and recurrence-free survival rate. And in localized forms, given the relatively low rates of long-term results, the choice of optimal treatment tactics is still debatable. Objective: to study the incidence and types of early complications after surgical and radiation treatment in the combined and complex treatment of cervical cancer (CC) stage IIb. The material for the study was retrospective data of 75 patients with histologically verified primary stage IIb cervical cancer diagnosis. We used the following methods: medical history, gynecological status, oncomarkers, histological examination from a cervical tumor, and pelvic ultrasonography. This article presents a retrospective analysis of early complications of cervical cancer after combined or complex treatment. The types and frequency of early complications depending on the method of treatment were studied. Results: in the group of patients after complex treatment, the most frequent complications were marked prolonged lymphorrhea in 38,8% and bladder atony in 16,6% of cases. Pre-clavian inflammatory infiltrates were observed only in 2 patients (11%). And in the combined treatment group the most frequent complications were radiodermatitis 25%, rectitis 37,5%, cystitis 43,7%, fistulas such as rectovaginal-vaginal and cyst-vaginal were observed in isolated cases. Analysis of the data demonstrates that complications after surgical and radiotherapy are different, and difficult to compare. The number and severity of complications in the complex treatment group is somewhat lower than in the combined treatment group and they are easily eliminated within a short time with minimal impact on the quality of life and condition of the patient, rather than in the control group, where complications after treatment remain for a long time (months and years).