THE CLINICAL COURSE OF NEONATAL PATHOLOGICAL JAUNDICE IN PRETERM AND FULL-TERM INFANTS

Abstract

The aim o f our research was to study the structure and features o f the clinical course of prolonged neonatal pathological jaundice. The object o f the study was newborns with pathological hyperbilirubinem ia: premature newborns (198 children) and full-term newborns (205 children). The severity o f the condition was assessed by changes in bilirubin, and the clinical manifestations o f jaundice were assessed on the Kramer, AVPU, and Glasgow scales. The data analysis revealed, that the structure o f prolonged pathological neonatal jaundice is dominated by hyperbilirubinem ia o f m ixed genesis, more often in com bination w ith intrauterine infection. Prem ature infants observed earlier, in term infants - a late diagnosis o f the disease. Clinical and laboratory assessm ent o f the patients ' condition allows us to conclude that prem ature infants have a m ore pronounced severity of the disease. However, the late diagnosis o f jaundice in full-term children causes high hyperbilirubinem ia during hospitalization.