PECULIARITIES OF COVID-19 PNEUMONIA IN CHILDREN WITH BRONCHIAL ASTHMA IN THE KYRGYZ REPUBLIC

DOI:

https://doi.org/10.54890/.v4i4.1068

Abstract

Purpose of the study: to conduct a retrospective analysis of the characteristics of the clinical picture of pneumonia with positive and negative tests for COVID-19 in children withbronchial asthma in children in the Kyrgyz Republic. Materials and methods. The case-control study  compared two groups aged 7 to 17 years who were ill from September 2020 to February 2021. The clinical and laboratory characteristics of Covid-19 pneumonia in children with bronchial asthma were studied. Results: The pattern of Covid-19 pneumonia differed from usual pneumonia in children with asthma (p<0.001). A correlation was identified between data in the anamnesis of children with bronchial asthma and Covid-19 diseases in children with existing bronchial asthma (p<0.001). Conclusions: Susceptibility to Covid-19 was observed in children with existing asthma. Children with uncontrolled asthma had an increased risk of hospitalization and more severe asthma.

Keywords:

children, bronchial asthma, pneumonia, Covid-19.

Author Biographies

S.E. Omusheva, Kyrgyz State Medical Academy named after I.K. Akhunbaev, National Center for Maternti and Childhood Wellfahre

Department of Hospital Pediatrics with course of Neonatology

B.T. Turdalieva, Kyrgyz State Medical Academy named after I.K. Akhunbaev, National Center for Maternti and Childhood Wellfahre

Department of Hospital Pediatrics with course of Neonatology

References

1. Chatziparasidis G, Kantar A. COVID-19 in Children with Asthma. Lung. 2021 Feb;199(1):7-12. https://doi.org/10.1007/s00408-021-00419-9

2. Boechat JL, Wandalsen GF, Kuschnir FC, Delgado L. COVID-19 and Pediatric Asthma: Clinical and Management Challenges. Int J Environ Res Public Health. 2021 Jan 26;18(3):1093. https://doi.org/10.3390/ijerph18031093

3. Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020 Jun;109(6):1088-1095. https://doi.org/10.1111/apa.15270

4. CDC COVID-19 Response Team. Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020. MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426. https://doi.org/10.15585/mmwr.mm6914e4

5. Баранов А.А., Намазова-Баранова Л.С., Хаитов Р.М. Согласованные рекомендации по ведению детей с аллергическими болезнями в период пандемии нового коронавируса SARS-CoV-2 (инфекции COVID-19). Педиатрическая фармакология. 2020;17(3):119–122. [Baranov A.A., Namazova-Baranova L.S., Xaitov P.M. Soglasovannye rekomendacii po vedeniy detei s allergicheskimi boleznyami v period pandemii novogo koranovirusa SARS-CoV-2 (infekciya COVID-19).Pediatricheskaya pharmakologia. 2020;17(3):119–122. (In Russ.)]. https://doi.org/10.15690/pf.v17i2.2097

6. Сулайманов Ш.А., Муратова Ж.К. Аллергические заболевания у детей в условиях пандемии новой корановирусной инфекции. Вестник КГМА им. И.К. Ахунбаева. 2021;3:92-105. [Sulaimanov Sh.A., Muratova Zh.K. Allergic diseases in children under conditions of new Coronavirus infection pandemic. Vestnik KGMA n.a. I.K. Akhunbayev. 2021;3:92-105. (In Russ.)].

7. Maltezou HC, Magaziotou I, Dedoukou X, Eleftheriou E, Raftopoulos V, Michos A et all. Children and Adolescents with SARS-CoV-2 infection: epidemiology, clinical course and viral loads. Pediatr Infect Dis J. 2020 Dec; 39(12):e388-e392. https://doi.org/10.1097/INF.0000000000002899

8. Rajapakse N, Dixit D. Human and novel coronavirus infections in children: a review. Paediatr Int Child Health. 2021 Feb;41(1):36-55. https://doi.org/10.1080/ 20469047.2020.1781356

9. Sansone NMS, Valencise FE, Bredariol RF, Peixoto AO, Lima Marson FA. Profile of coronavirus disease enlightened asthma as a protective factor against death: An epidemiology study from Brazil during the pandemic. Front Med (Lausanne). 2022 Nov 29;9:953084. https://doi.org/10.3389/fmed.2022.953084

10. Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M et all. A compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy. 2020 Oct;75(10):2503-2541. https://doi.org/10.1111/all.14449

11. Gao YD, Agache I, Akdis M, Agache I, Akdis M, Alves-Correia M et all. The effect of allergy and asthma as a comorbidity on the susceptibility and outcomes of COVID-19. Int Immunol. 2022 Mar 25;34(4):177-188. https://doi.org/10.1093/intimm/dxab107

12. Rao S, Hurst JH, Zhao C, Goldstein BA, Thomas L, Lang JE et all. Asthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents. Pediatrics. 2022 Jun 1;149(6):e2021056164. https://doi.org/10.1542/peds.2021-056164

13. Ramakrishnan RK, Al Heialy S, Hamid Q. Implications of preexisting asthma on COVID-19 pathogenesis. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L880-L891. https://doi.org/10.1152/ajplung.00547.2020

14. Munblit D, Greenhawt M, Brough HA, Pushkareva A, Karimova D, Demidova A et al. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics. Pediatr Allergy Immunol. 2022 Oct; 33(10):e13851. https://doi.org/10.1111/pai.13851

15. Boechat JL, Wandalsen GF, Kuschnir FC, Delgado L. COVID-19 and Pediatric Asthma: Clinical and Management Challenges. Int J Environ Res Public Health. 2021 Jan 26;18(3):1093. https://doi.org/10.3390/ijerph18031093

16. Ghosh S, Das S, Mondal R, Abdullah S, Sultana Sh, Singh S et all. A review on the effect of COVID-19 in type 2 asthma and its management. Int Immunopharmacol. 2021 Feb; 91:107309. https://doi.org/10.1016/j.intimp.2020.107309

17. Papadopoulos NG, Custovic A, Deschildre A, Mathioudakis AG, Phipatanakul W, Wong G et all. Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2592-2599.e3. https://doi.org/10.1016/j.jaip.2020.06.001

18. Sokolowska M, Lukasik ZM, Agache I, Akdis CA, Akdis D, Akdis M et all. Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI). Allergy. 2020 Oct;75(10):2445-2476. https://doi.org/10.1111/all.14462

Published

2023-12-15

How to Cite

Омушева, С., and Б. Турдалиева. “PECULIARITIES OF COVID-19 PNEUMONIA IN CHILDREN WITH BRONCHIAL ASTHMA IN THE KYRGYZ REPUBLIC ”. Euroasian Health Journal, vol. 4, no. 4, Dec. 2023, pp. 134-41, doi:10.54890/.v4i4.1068.

Issue

Section

QUESTIONS OF PEDIATRY