CLINICAL AND LABORATORY CHARACTERISTICS OF ACUTE NOSOCOMIAL ROTA VIRAL INFECTION OF AN EARLY AGE CHILDREN
DOI:
https://doi.org/10.54890/.v4i4.1063Abstract
We examined 45 young children with nosocomial rotavirus infection who received inpatient treatment at the Republican Clinical Infectious Hospital (RCIH). Clinical and laboratory characteristics of nosocomial rotavirus infection in young children are given. As a result of the study, nosocomial rotavirus infection is often (86.4%) registered among children of the first year of life who are on artificial and mixed feeding. Basically, children with rotavirus infection were admitted in the cold season and were residents of Bishkek (64.3%), by gender showed that both boys (50%) and girls (50%) were equally ill. The disease began acutely with symptoms of gastroenteritis and proceeded mainly in severe form (73.8%) due to the formation of mixinfection and complications. It should be noted that the stay in other hospitals in children under one year lasted for 7.3±2.4 days, in children under 3 years 3.6±1.2 days. The diagnosis was confirmed by express diagnostic methods: a rota test in 78.5% of patients and PCR analysis of faeces. For timely diagnosis of nosocomial RVI, it is necessary to use express diagnostics by latex agglutination reaction (rota test) and PCR analysis.
Keywords:
children, nosocomial rotavirus infection, gastroenteritis, clinic, diagnosis, treatment.References
1. Ермоленко К.Д., Лобзин Ю.В., Гончар Н.В. Вирусные гастроэнтериты у детей: современные представления об эпидемиологии и профилактике. Журнал инфектологии. 2015;7(3):22-32. [Ermolenko KD, Lobzin YuV, Gonchar NV. Viral gastroenteritis in children: modern concepts of epidemiology and prevention. Journal Infectology. 2015;7(3):22-32. (In Russ.).] https://doi.org/10.22625/2072-6732-2015-7-3-22-32
2. Асилова М.У., Мусабаев Э.И., Убайдуллаева Г.Б. Вирусные диареи в структуре острых кишечных инфекций у детей. Журнал инфектологии. 2011; 3(3):56-59. [Asilova MU, Musabaev EI, Ubaydullaeva GB. Viral diarrhea in structure of acute intestinal infections in children. Journal Infectology. 2011;3(3):56-59. (In Russ.).] https://doi.org/10.22625/2072-6732-2011- 3-3-56-59
3. Маянский Н.А., Маянский А.Н., Куличенко Т.В. Ротавирусная инфекция: эпидемиология, патология, вакцинопрофилактика. Вестник РАМН. 2015;1:47-55. [Mayansky N.A., Mayansky A.N., Kulichenko T.V. Rotavirus infection: epidemiology, pathology, vaccination. Bulletin of the Russian Academy of Medical Sciences. 2015; 1:47-55. (In Russ.).]
4. Духовлинов И.В., Богомолова Е.Г., Федорова Е.А. Исследование протективной активности кандидатной вакцины против ротавирусной инфекции на основе рекомбинантного белка FHCVP6VP8. Медицинская иммунология. 2016; 18(5):417-424. [Dukhovlinov I.V., Bogomolova E.G., Fedorova E.A. Investigation of the protective activity of a candidate vaccine against rotavirus infection based on the recombinant protein FHCVP6VP8. Medical immunology. 2016; 18(5):417-424. (In Russ.).]
5. Gomez-Rial et al Rotavirus infection beyond the gut Infection and Drug Resistance 2019; 12:55–64.
6. Troeger Christopher, Blacker Brigette F, Khalil Ibrahim A, Rao Puja C, Cao Shujin, Zimsen Stephanie R M, Albertson Sam Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016; 18:1211-1228.
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