THE USE OF CHITOSAN GEL FOR POST-TRAUMATIC PERFORATION OF THE EARDRUM

DOI:

https://doi.org/10.54890/1694-8882-2025-2-103

Abstract

The purpose of this work is to track and evaluate the effect of chitosan on tissue regeneration in post-traumatic eardrum perforation caused by mechanical damage, barotrauma, or infectious processes. Chitosan, a biopolymer with regenerative and anti-inflammatory properties, was used in the study. Since acute traumatic perforation of the eardrum may involve the structures of the middle and inner ear in the pathological process, it is advisable to use both subjective and objective methods to assess hearing dynamics. audiometry (a subjective technique) in adults is a routine method of assessing auditory function in cases of damage to both the sound-conducting and sound-receiving parts of the auditory system. In the article, the authors provide data on the use of chitosan gel for post-traumatic perforation of the eardrum, which is used for the first time in Kyrgyzstan as a method of tissue regeneration, which leads to its restoration, as well as the results of comparison with the control group. As a result of the study, it was noted that the use of chitosan in eardrum injury opens up prospects for the development of new treatment methods that promote rapid and safe tissue healing, as well as reduce inflammatory reactions and prevent complications.

Keywords:

perforation of the eardrum, chitosan, tinnitus, hearing loss, restoration of the eardrum

Author Biographies

T.M. Zakirov, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Otolaryngology

E.S. Kulieva, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Otolaryngology

M.Sh. Zheenbekova, Kyrgyz State Medical Academy named after I.K. Akhunbaev

Department of Otolaryngology

References

1. Полякова С.Д., Батенева Н.Н., Попова Б.А. Комплексный подход к диагностике и лечению травматических отитов. Российская оториноларингология. 2009;41(4):114-118.

2. Староха А.В., Давыдов А.В., Кочеров С.Н. Способ мирингопластики без заполнения барабанной полости рассасывающимися материалами. Российская оториноларингология. 2012;58(3):115-119.

3. Гуров А.В., Крюков А.И., Левина Ю.В., Бахтин А.А., Дубовая Т.К., Мурзаханова З.В. Регенерация барабанной перепонки и оценка динамики слуха при острой травматической перфорации барабанной перепонки после аппликации плазмы крови, обогащенной тромбоцитарными факторами роста. Вестник оториноларингологии. 2021;86(4):23–30. https://doi.org/10.17116/otorino20218604123

4. Насыров В.А., Иаева Т.А., Исламов И.М. Практическое руководство по аудиологии. Бишкек. 2014:110-112.

5. Onal K, Kazikdas KC, Uğuz MZ, Gursoy ST. A multivariate analysis of otological, surgical and patient-related factors in determining success in myringoplasty. Clinical Otolaryngology. 2005;30(2):115-120. https://doi.org/10.1111/j.1365-2273.2004.00947.x

6. Lee D, Honrado C, Har-El G, Goldsmith A. Pediatric temporal bone fractures. Laryngoscope. 1998;108(6):816-821. https://doi.org/10.1097/00005537199806000-00008

7. Туманов В.П., Пальчун В.Т., Поматилов А.А., Полякова Е.В., Захарова А.В., Ярыгин В.Н. Современные клеточные технологии при лечении больных с травмой барабанной перепонки после минно-взрывных повреждений. Вестник оториноларингологии. 2006;2:92-95.

8. Кротов Ю.А. Мирингопластика при обширных перфорациях барабанной перепонки. Вестник оториноларингологии. 2001;5:57-59.

9. Шелеско Е.В., Черникова Н.А., Фомочкина Л.А., Лебедев М.А., Никонова С.Д., Доронина В.А. и др. Принципы диагностики и лечения шума в ушах. Журнал неврологии и психиатрии. 2021;121(11):99-105. https://doi.org/10. 17116/jnevro202112111199

10. Изаева Т.А., Исмаилова А.А., Беднякова Н.Н. Особенности лечения тиннитуса при слухопротезировании пациентов с сенсоневральной тугоухостью. Вестник КРСУ. 2022;22(9):41-44. https://doi.org/10.36979/1694-500X-2022-22-9-41-44

Published

2025-08-07

How to Cite

1.
Закиров Т, Кулиева Э, Жеенбекова М. THE USE OF CHITOSAN GEL FOR POST-TRAUMATIC PERFORATION OF THE EARDRUM. ЕЖЗ. 2025;2(2):103-109. doi:10.54890/1694-8882-2025-2-103

Issue

Section

QUESTIONS OF OTORHINOLARYNGOLOGY