CONGENITAL PATHOLOGY OF NEWBORNS IN UKRAINE AND ITS PROPHYLAXIS
Abstract
Resume: The investigation tasks were to observe congenital malformation prevalence in the regions o f Ukraine, to indicate their risk factors and to estimate the efficacy o f their primary and secondary prophylaxis.
According to the Ministry of Healthcare data the frequency of congenital malformations was estimated among born alive, stillborne and genetically caused abortions during 2002-2011. Case-control study was performed.
Congenital malformations prevalence among born alive, still-borne and genetically caused abortions was (26,83±0,08) %o during 2002-2011, it was fluctuated in different regions. Congenital malformations priority risk factors were underlined; they were mother’s chronicle infectious and non-infectious diseases (including endocrine diseases), smoking, professional hazards and age.
The efficacy of congenital malformations primary and secondary prophylaxis was shown.
Keywords:
congenital malformations, prevalence, risk factors, primary and secondary prophylaxis.References
1. Negro-Vilar A. Stress and other environmental factors affecting fertility in men and women: overview / A. Negro-Vilar // Environ. Health Perspect. - 1993. - V. 101, Suppl. 2. - P. 59-64.
2. A Review of Environmental Risk Factors for Congenital Anomalies, www.eurocat.ulster. ac.uk/pubdata.
3. Здоровье населения Украины: влияние генетических процессов / А.М Сердюк, О.И. Тимченко, В.В. Елагин [ и др.] // Журнал АМН Украины. - 2007. Т. 13, № 1 , - С. 78-92 (укр.).
4. EUROCAT Surveillance of congenital anomalies in Europe, 1980-1999: EUROCAT Report 8. - University of Ulster, 2002. - 280 p.
5. EUROCAT Statistical Monitoring Report- 2007 (Uploaded to EUROCAT website May 2010). www.eurocat-network.eu.
6 . EUROCAT Statistical Monitoring Report- 2009 (Uploaded to EUROCAT website January 2012) wvf^v.eurocat-network.eu
7. Генофонд и здоровье населения: методология оценки риска от мутагенов окружающей среды, пути профилактики генетический обусловленной патологии / А.М. Сердюк, О.И. Тимченко, Н.Г. Гойда [ и др.]. - К., 2003. - 191 с. (укр.)
8. Елагин В.В. Научные основы усовершенствования медико-генетической помощи населению Украины: автореф. дис. на соискание ученой степени д.мед. наук.: спец.:14.02.03 „социальная медицина” / В.В. Елагин - К., 2 0 0 5 .-4 0 с. (укр.).
9. Пренатальная диагностика наследственных и врожденных болезней / Под ред. Э.К. Айламазяна, В.С.Баранова. - М.: МЕДпресс-инфор, 2007. —416 с.