COMPARATIVE CHARACTERISTICS OF BRUCELLA ISOLATED IN THE KYRGYZ REPUBLIC
DOI:
https://doi.org/10.54890/.v1i1.1297Abstract
The article provides data on the distribution of Brucella species among humans and farm animals circulating in the Kyrgyz Republic. According to the results of molecular genetic analyses performed by different authors, Brucella cultures isolated from humans were attributed only to B. melitensis species, isolates isolated from farm animals indicated circulation of both Brucella species. Of the 443 strains obtained from small ruminants 427 (96.3%) were identified as B. melitensis and 16 (3.6%) strains were assigned to B. abortus. On typing of 30 brucella strains from cattle, 11 (37%) were attributed to B. abortus and 19 samples (63%) were attributed to B. melitensis. Also, data on migration of B. melitensis to cattle and migration of B. abortus to small ruminants are presented. B. melitensis migration to cattle and B. abortus migration to small ruminants. The results of full generation sequences of the brucellosis strains isolated from humans were identified as B. melitensis and showed the identity of the brucellosis pathogen strains with the strains circulating in the Eastern Mediterranean countries with the greatest similarity to the strains from Turkmenistan, Iran and Turkey.
Keywords:
brucellosis, genotyping, Brucella melitensis, Brucella abortus, Kyrgyzstan.References
1. Писаренко С.В., Ковалев Д.А., Хачатурова А.А., Волынкина А.С., Русанова Д.В., Куличенко А.Н. Филогеография штаммов Brucella melitensis на основе анализа SNP полных геномов. Бактериология. 2016;1(1):73-79. https://doi.org/10.20953/2500-1027-2016-1-73-79
2. Ficht T. Brucella taxonomy and evolution. Future Microbiol. 2010;5(6):859-66. https://doi.org/10.2217/fmb.10.52
3. Roth F, Zinsstag J, Orkhon D, Chimed-Ochir G, Hutton G, Cosivi O, et al. Human health benefits from livestock vaccination for brucellosis: Case study. [published correction appears in Bull World Health Organ. 2004 Jan;82(1):76]. Bull World Health Organ. 2003;81(12):867-876.
4. Охапкина В.Ю., Пяткова Н.В., Павлов Д.Л., Суслопаров А.А. Эпидемическая опасность бруцеллеза в современных условиях Эпидемиология и вакцинопрофилактика. 2016;15(3):15-22.
5. Атамбекова Ж.А., Акматова Э.К., Чегиров С.Б., Камарли А.А. Определение типа бруцелл с применением amos-pcr. Вестник Алтайского государственного аграрного университета. 2016;10(144):107-110.
6. Чегиров С. Б., Нургазиев Р.З., Келдибекова З.С., Турсумбетов М.С. Типизация Brucella melitensis и abortus до видовой принадлежности с применением видоспецифических праймеров. Известия ВУЗов Кыргызстана. 2014;3:85-86.
7. Чегиров С.Б. Молекулярно-генетическогое типирование бруцелл, циркулирующих в фермерских хозяйствах Ак-Талинского района Нарынской области. Наука и новые технологии. 2013;5:135-138.
8. Kasymbekov J, Imanseitov J, Ballif M, Schürch N, Paniga S, Pilo P, et al. Molecular epidemiology and antibiotic susceptibility of livestock Brucella melitensis isolates from Naryn Oblast, Kyrgyzstan. PLoS Negl Trop Dis. 2013;7(2):e2047. https://doi.org/10.1371/journal. pntd.0002047
9. Турсумбетов М.С., Чегиров С.Б., Кельдибекова З.С. Межвидовая миграция возбудителя бруцеллеза среди яков. Вестник Красноярского государственного аграрного университета. 2021;3(168):127-132.
10. Kydyshov K, Usenbaev N, Berdiev S, Dzhaparova A, Abidova A, Kebekbaeva N,. et al. First record of the human infection of Brucella melitensis in Kyrgyzstan: evidence from whole-genome sequencing-based analysis //Infectious Diseases of Poverty. 2022;11(1):120. https://doi.org/10.1186/s40249-022-01044-1
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