КОМПЛЕКСНОЕ ЛЕЧЕНИЕ ОСТРОГО ДЕСТРУКТИВНОГО ПАНКРЕАТИТА (ОБЗОР ЛИТЕРАТУРЫ)
Аннотация
Острый деструктивный панкреатит – грозное хирургическое заболевание, представляющее серьезную проблему из-за своей географической распространенности, тяжелая форма которого связана с высокой заболеваемостью и смертностью. При этом летальность в зависимости от объема воспалительного процесса поджелудочной железы и тяжести течения самой патологии сохраняется на уровне 20% и выше. Целью исследования было изучение и обобщение литературных данных опыта исследователей за последние 10 лет, посвященных поиску наиболее эффективных методов хирургического лечения в комплексе с медикаментозной терапией острого деструктивного панкреатита. Для поиска информации были использованы следующие базы данных: Pubmed, MEDLINE, Embase, Springer, ScienceDirect, Cochraine Library, а также публикации из журналов стран СНГ и РК. После комплексной и стандартизированной оценки учитывались только исследования в которых был представлен опыт комплексного лечения острого деструктивного панкреатита, включавшего непрерывное регионарное артериальное введение лекарственных средств.
Ключевые слова:
острый деструктивный панкреатит (ОДП), панкреонекроз, непрерывная регионарная артериальная инфузия (НРАИ), ингибитор протеаз, улиностатин.Библиографические ссылки
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